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Long-term Consequences of Bereavement in Children, Adolescents and Young Adults

Completed
Conditions
Bereavement
Registration Number
NCT01453699
Lead Sponsor
Danish Cancer Society
Brief Summary

The purpose of this study is to examine how the death of a parent as a child, adolescent or young adult affects health and psychosocial wellbeing in adult life and to evaluate the impact in adult life of counseling to children, adolescents and young adults who lost a parent.

Detailed Description

Early parental death experienced by 4% of the children in Western countries, is considered to be the most stressful and potentially harmful childhood life event and the health consequences may depend on the nature of the bereavement (e.g. relationship with bereaved), as well as by interpersonal (e.g. social support), intrapersonal (e.g. age and genetics), appraisal and coping factors. Studies have shown that children and adolescents have a greater risk of getting a psychiatric diagnose as well as psychological and social problems. Despite of the obvious consequences of losing a parent, there is a lack of systematic studies on the consequences later in life as well as studies that evaluate the counseling possibilities the children and adolescents are offered.

The study will investigate:

1. Long-term health effects of experiencing parental death as a child adolescent or young adult. Focus will be on psychiatric outcomes including depression, severe cardiovascular disease, suicide, suicide attempts, psychological well-being and health related behavior.

2. Long term effects of experiencing parental death as a child, adolescent or young adult on socioeconomic outcomes as education, employment, marital status/ cohabitation status and number of children/age when having children.

3. The long-term psychosocial and behavioral impact of psychological intervention programmes to children, adolescents and young adults who have experienced the death of a parent. Focus will be on: Depressive symptoms, quality of life, posttraumatic stress disorder, life style, relationship functioning, grief and spirituality.

A nationwide register based cohort of people born in Denmark will be established. Long-term health effects and socioeconomic outcomes of experiencing parental death will be based on nationwide clinical and administrative registries. Exposure is defined as experiencing the death of a parent before age 30. The long-term psychosocial and behavioral impact of psychological intervention programmes will be based on a combination of questionnaire data and data from registries.

The part of the study using data from registries will be based on the nationwide cohort. The questionnaire based part of the study will include 3 groups selected from the nationwide cohort:

1. Persons who have lost a parent and participated in intervention programmes (identified through counseling centers),

2. Persons who have lost a parent, and not participated in intervention programmes (randomly selected matched on age and gender) and

3. Persons who have not lost a parent (randomly selected matched on age and gender).

An invitation letter will be send to the 3 groups (5500 persons) by mail, and they will be asked to complete one questionnaire online.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1225660
Inclusion Criteria
  • persons born in Denmark
Exclusion Criteria

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Severe cardiovascular diseasePaticipants will be followed from age 18 until date of first hospitalization for severe cardiovascular disease, death, first emigration or end of follow up, an expected average of 15 years

The Danish National Patient Register

Quality of lifeParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

SF-36, Self-reported questionnaire

Hospitalization for affective disorderPaticipants will be followed from age 15 until date of first hospitalization for an affective disorder, death, first emigration or end of follow up, an expected average of 12 years

Danish Psychiatric Central Register

Use of antidepressive medicationPaticipants will be followed from age 20 until date of second independantly prescription of antidepressive medication, death, first emigration or end of follow up, an expected average of 9 years

The Danish National Prescription Registry

EmploymentEmployment status at age 30, death, first emigration or end of follow-up, an expected average of 8 years.

The Register-based System of Demographics and Social Statistics in Denmark

Complicated griefParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Inventory of Complicated Grief/ Prolonged Grief Disorder (PG-13) and Centrality of Event Scale, Self-reported questionnaire

PTSDParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Harvard Trauma Questionnaire (HTQ), Self-reported questionnaire

Depressive symptomsParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

The Center for Epidemiological Studies Depression Scale (CES-C)

SuicidePaticipants will be followed from age 18 until date of suicide, other causes of death, first emigration or end of follow up, an expected average of 15 years

Danish Register of Causes of Death

ExistentialityParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Posttraumatic Growth Inventory (PTGI, Self-reported questionnaire

Education levelParticipants will be followed from age 18 until highest attained educational level, death, first emigration or end of follow up, an average of 20 years

The Register-based System of Demographics and Social Statistics in Denmark

Secondary Outcome Measures
NameTimeMethod
Relationship functioningParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Quality of relationship and intimacy, Self-reported questionnaire

Support when losing a parentParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Self-report items

Lifestyle (smoking, alcohol, exercise)Participants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Self-reported questionnaire

CopingParticipants will be answering the questionnaire once (not at a specifik age but between 18-40 years)

Brief cope, Self-reported questionnaire

Trial Locations

Locations (1)

Department of Psychosocial Cancer Research, Institute of Cancer Epidemiology, Danish Cancer Society

🇩🇰

Copenhagen, Denmark

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