A Comparative Study of Three Airway Clearance Techniques With Different Autonomy Degrees in Non Cystic Fibrosis Bronchiectasis: Randomized Cross-over Trial.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 31
- 试验地点
- 1
- 主要终点
- Weight of sputum expectorated during each airway clearance therapy session
研究概览
简要总结
Study design: a randomized, crossover trial. Each patient performed three different airway clearance techniques (Autogenic drainage, slow expiratory with glottis opened in lateral posture [ELTGOL], temporary- positive expiratory pressure [T-PEP] with not similar autonomy degree in a randomized order. Each technique were applied in 3 sessions during one week at alternate days (Monday /Wednesday/Friday or Tuesday/Thursday/Saturday). The time spent in each bronchial session was 40 minutes. Seven days were the wash-out time period between the different techniques.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Non Cystic Fibrosis bronchiectasis diagnosed by High Resolution Computed Tomographic
- •Mean sputum production ≥ 15 ml /24h
- •Clinical stability in the last 6 weeks
- •Not carrying out regular chest physiotherapy
- •Forced expiratory volume in 1 second ≥ 30% pred. ; Forced Vital Capacity ≥ 45% pred. and peak expiratory flow >270 L/s
排除标准
- •Smoker or non-smoker form less than 2 years
- •Cystic fibrosis
- •Active tuberculosis or sarcoidosis
研究组 & 干预措施
Autogenic drainage
All patients performed all interventions in a randomized order. Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes
干预措施: Autogenic drainage (Other)
Slow expiration with glottis opened in lateral posture
All patients performed all interventions in a randomized order.Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes
干预措施: Slow expiration with glottis opened in lateral posture (Other)
Temporary-Positive Expiratory Pressure
All patients performed all interventions in a randomized order. Each technique was applied in 3 non consecutively sessions during one week. The time spent during the session was 40 minutes
干预措施: Temporary-positive expiratory pressure (Other)
结局指标
主要结局
Weight of sputum expectorated during each airway clearance therapy session
时间窗: 40 minutes
Wet weight sputum production were recollected in one pre-weighted containers. It was measured in grams.
Weight of sputum expectorated 24 hours post each bronchial session
时间窗: 24 hours
Wet weight sputum production were recollected in one pre-weighted containers. It was measured in grams.
次要结局
- Saint George Respiratory Questionnaire (SGRQ)(Change from baseline at 5 weeks)
- Leicester Cough Questionnaire (LCQ)(Changes from baseline arm to 1 week)
研究者
Beatriz Herrero
Physiotherapist
Hospital Clinic of Barcelona