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临床试验/CTRI/2024/04/065713
CTRI/2024/04/065713尚未招募不适用

Change in upper airway related ultrasonographic parameters during percutaneous nephrolithotomy under prone position- A prospective observational cohort study

未提供1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2024年4月25日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
60
试验地点
1
主要终点
To evaluate the intraoperative change in upper airway related ultrasonographic parameters after anaesthesia induction in patients undergoing percutaneous nephrolithotomy under prone position

研究概览

简要总结

Surgery under prone position is often a necessity when accessing posterior anatomic structures like spine, retroperitoneum and upper urinary tracts. However, prone position is associated with position related oedema, visual loss, peripheral nerve palsies, pressure sores, cardiovascular compromise, compartment syndrome, oropharyngeal edema, macroglossia, sublingual hematoma which have to be assessed increasingly to be able to predict early and to have adequate prophylactic measures. Ultrasound is a quick, accessible and reliable tool which can be used in operating rooms and can visualize anatomical structures in the supraglottic, glottic and subglottic regions. There is sufficient evidence to advocate utility of airway ultrasound to predict difficult intubation, but literature on intraoperative change in these parameters is sparse. we hypothesize that change in upper airway during prone position may be reflected as significant change in upper airway related ultrasound parameters namely tongue thickness (TT), tongue volume (TV), skin to hyoid distance (SH), skin to thyrohyoid membrane distance (ST). It may help in predicting ease of extubation at the end of surgery and estimating the associated risk of postoperative airway related complications in patient undergoing surgery under prone position. We aim to investigate the intraoperative change in upper airway related ultrasonographic parameters in patients with unanticipated difficult airway, undergoing percutaneous nephrolithotomy under prone position.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • ASA grade 1 and 2 Patients undergoing percutaneous nephrolithotomy surgery under general anaesthesia.

排除标准

  • BMI greater than 35kg/m2 Pregnant women and parturients Patients with predicted difficult intubation Patients with abnormal pharynx or anatomy.

结局指标

主要结局

To evaluate the intraoperative change in upper airway related ultrasonographic parameters after anaesthesia induction in patients undergoing percutaneous nephrolithotomy under prone position

时间窗: Measured at timepoints T2 and T3. | Where, T2- Just after initiation of the mechanical ventilation after confirmation of the endotracheal tube placement | T3- Just after turning the patient to supine position at the end of the surgery

次要结局

  • To correlate the intraoperative duration of proning with change in intraoperative upper airway related ultrasonographic parameters after anaesthesia induction in patients undergoing percutaneous nephrolithotomy under prone position(Measured at timepoints T2, T3 and whole of intraoperative period.)
  • To evaluate various factors that may be associated with intraoperative change in upper airway related ultrasonographic parameters after anaesthesia induction in patients undergoing percutaneous nephrolithotomy under prone position.
  • To correlate intraoperative change in upper airway related ultrasonographic parameters with ease of extubation after undergoing percutaneous nephrolithotomy under prone position(Measured at timepoints T2, T3 and during extubation.)
  • To correlate intraoperative change in upper airway related ultrasonographic parameters with airway complications during the first 48 hours of postoperative period after percutaneous nephrolithotomy under prone position(Measured at timepoints T2, T3 and for 48 hours postoperatively.)

研究者

发起方
未提供
责任方
Principal Investigator
主要研究者

Darshan GowdaT A

All India Institute Of Medical Sciences Rishikesh

研究点 (1)

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