Does providing low-medium flow of oxygen to the non-ventilated lung during one-lung ventilation prevent lung injury?
- Conditions
- Prevention of acute lung injury in patients undergoing video-assisted thoracoscopic surgery for lung tumor requiring one-lung ventilationRespiratory
- Registration Number
- ISRCTN92523174
- Lead Sponsor
- Zhongnan Hospital of Wuhan University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 60
1. Physical status I or II according to the American Society of Anesthesiologists
2. Age 18-64 years
3. Scheduled to undergo video-assisted thoracoscopic surgery requiring one-lung ventilation (OLV) for the treatment of lung tumor
1. Surgery for more than 4 h
2. Need to stop single lung ventilation during surgery to restore dual lung ventilation to maintain oxygen saturation >90%
3. Patients with immune disease, upper respiratory tract infection, adrenal dysfunction, recent radiotherapy or chemotherapy, pleural effusion, asthma or oral hormonal therapy within 3 months prior to surgery
4. Preoperative pulmonary function tests measured values lower than the minimum required value of various lung resection preoperative pulmonary function test (FEV1 <70% of predicted value)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method