The Relationship Between CD138 Count of Endometrium and Reproductive Outcome
Not Applicable
Completed
- Conditions
- Infertility
- Interventions
- Procedure: Endometrial biopsies
- Registration Number
- NCT03689101
- Lead Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
- Brief Summary
It's well known, endometritis affects reproductive outcomes. Though CD138 counting as one new diagnosis measure for endometritis, diagnostic criterion of this measure isn't consistent. And if the CD138 counting is correlation to the outcome of reproductive is not clear.
Firstly, This study aims to explore the relationship between endometrial CD138 count and pregnancy outcome following frozen embryo transfer in natural cycles. Secondly , the investigators want to find a cut-off value which is related to reproduction outcome.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 148
Inclusion Criteria
- age between20 and 38 years;
- regular menstrual cycles;
- body mass index (BMI) ranged from 18 to 25
Exclusion Criteria
- uterine abnormalities;
- intrauterine adhesions（moderate - severe）, advanced endometriosis, adenomyosis, untreated hydrosalpinx, uterine fibroids (submucosal fibroids, nonmucosal fibroids >4.0 cm and/or endometrial pressure)
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Endometrial biopsies Endometrial biopsies Endometrial biopsy was performed precisely 7 days after LH surge (LH+7) to count endometrial CD138.
- Primary Outcome Measures
Name Time Method CD138 counting 7 days after LH surge (LH+7) clinical pregnancy rate about 28 days after embryo transfer
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Reproductive & Genetic Hospital of CITIC-XIANGYA
🇨🇳Changsha, Hunan, China