Visual Stimulation for Pain Relief

Not Applicable

Completed

• Conditions: Pain
• Interventions: Behavioral: Visual Stimulation

• Registration Number: NCT06276881
• Lead Sponsor: Dandelion Science

Brief Summary

The goal of this study is to investigate a novel neuromodulatory approach utilizing visual stimulation to impact pain perception in healthy participants.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-03
• Primary Completion: 2022-12-28
• Study Completion: 2023-05-01
• Study First Submitted: 2024-02-12
• Study First Submitted QC: 2024-02-17
• Study First Posted: 2024-02-26
• Results First Submitted: 2024-03-08
• Results First Submitted QC: 2024-03-08
• Results First Posted: 2024-04-03
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-05
• Last Update Posted: 2024-08-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 75

Inclusion Criteria

• Participants of both sexes
• Participants of diverse ethnic and racial backgrounds
• Participants who speak, read, and understand English and are willing and able to provide written informed
• 18 to 50 years old

Exclusion Criteria

• Participants with neurologic, endocrine, renal, gastrointestinal, and chronic pain disease
• Participants who use unprescribed drugs or medications
• Chronically medicated participants
• Participants with photosensitivity and epileptic seizures
• Participants who have undergone major surgery within two months of the experiment date
• Participants with cardiac disorders
• Participants who are pregnant
• Prisoners
• Participants who are unable to provide consent
• Participants diagnosed with a psychiatric disorder that is likely to interfere with the conduct of the study
• Participants with implanted electronic devices of any kind, including pace-makers, electronic infusion pumps, stimulators, defibrillators

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Healthy Controls	Visual Stimulation	-

Primary Outcome Measures

Name	Time	Method
Event-related Potential (ERP)	Up to 2 hours	Evoked event-related neural response to contact heat perception measured by EEG (electroencephalography), P300 component
Visual Analog Scale (VAS) Score	Up to 2 hours	Standard computerized scale of perceived pain level. The scale ranges from 0 to 100, a score of "0" indicating "No Pain" and a score of "100" indicating "Most Pain". Higher score indicates a worse outcome as perceived pain is increasing, lower score indicates a better outcome as perceived pain is decreasing.

Trial Locations

Locations (1)

Dandelion Science; 🇺🇸 Hoboken, New Jersey, United States