on-invasive assessment of oral leukoplakia and adjacent tissue

Recruiting

• Conditions: leukoplakia; precursor stage of oral cancer; 10027656

• Registration Number: NL-OMON52402
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 6 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 150

Inclusion Criteria

Patient presents with oral leukoplakia.

Exclusion Criteria

Histopathological examination of biopsy specimen reveals carcinoma

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Abnormal area determined by narrow band imaging in comparison with excision<br /><br>borders.<br /><br>Presence of genetic abnormalities within and adjacent to the visible lesion.<br /><br>Time until leukoplakia recurrence.<br /><br>Time until malignant progression of the leukoplakia.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Identification of specific genetic abnormalities.</p><br>