Longitudinal Evaluation Of Sarkopenia-Related Parameters After Bariatric Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Change in Femoral Muscle Thickness
研究概览
简要总结
This prospective observational study aims to evaluate longitudinal changes in sarcopenia-related parameters in patients undergoing bariatric surgery. Obesity and rapid weight loss following bariatric surgery may lead to changes in muscle mass, muscle strength, and physical performance, which are important components of sarcopenia.
Participants will be evaluated before bariatric surgery and during postoperative follow-up visits. Muscle thickness will be assessed using ultrasonography of the femoral muscles. Muscle strength and physical performance will be evaluated using handgrip strength, the 5-meter walk test, and the five-times sit-to-stand test.
The study aims to investigate the effects of bariatric surgery on muscle function and physical performance over time and to contribute to the early identification of sarcopenia risk in this patient population.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults aged 18 years and older
- •Patients scheduled to undergo bariatric surgery
- •Ability to participate in physical performance tests
- •Ability to provide written informed consent
排除标准
- •Presence of neurological or musculoskeletal disorders affecting muscle strength or physical performance
- •Severe cardiopulmonary disease limiting physical activity
- •Active malignancy
- •Pregnancy
- •Inability to complete study assessments
- •Refusal to participate in the study
结局指标
主要结局
Change in Femoral Muscle Thickness
时间窗: Preoperative baseline, postoperative 1st month, 3rd month, 6th month, and 12th month assessments
Femoral muscle thickness will be assessed using ultrasonography before bariatric surgery and during postoperative follow-up visits to evaluate longitudinal changes associated with sarcopenia.
次要结局
- Change in Handgrip Strength(Preoperative baseline, postoperative 1st month, 3rd month, 6th month, and 12th month assessments)
- Change in Five-Times Sit-to-Stand Test Performance(Preoperative baseline, postoperative 1st month, 3rd month, 6th month, and 12th month assessments)
研究者
Hatice Zehra FERHATLAR
Principal Investigator
Kanuni Sultan Suleyman Training and Research Hospital