Skip to main content
Clinical Trials/NCT06494618
NCT06494618
Recruiting
Not Applicable

The Effects of Botulinum Toxin Type a Injection Combined with RESWT in Lower Extremity Spasticity in Children with Cerebral Palsy

Istanbul Medeniyet University1 site in 1 country20 target enrollmentMarch 2025

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cerebral Palsy, Spastic
Sponsor
Istanbul Medeniyet University
Enrollment
20
Locations
1
Primary Endpoint
Modified Aschworth Scale
Status
Recruiting
Last Updated
last year

Overview

Brief Summary

This study aimed to check and compare the effects of botulinum toxin injection combined with shock wave therapy versus botulinum toxin injection only for lower extremity spasticity in children with cerebral palsy

Detailed Description

20 pediatric patients diagnosed with cerebral palsy who received botulinum toxin type A injection for lower extremity spasticity were divided into two groups. The first group will receive only conventional treatment after the injection, while the second group will receive extracorporeal shockwave therapy for injected muscles. The shock wave therapy is planned as 3 sessions per week, starting one week after the injection. Patients will be compared in terms of MAS scores, MTS scores, passive joint range of motion, modified timed up and go test, pain scores, (faces pain scale-revised) and Goal Attainment Scaling scores. Patients will be evaluated 1 week, 1 month and 3 months after the injection with pre-injection data.

Registry
clinicaltrials.gov
Start Date
March 2025
End Date
June 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Istanbul Medeniyet University
Responsible Party
Principal Investigator
Principal Investigator

Bilinç Doğruöz Karatekin

Bilinc Dugruoz Karatekin, M.D., Department of Physical Medicine and Rehabilitation

Istanbul Medeniyet University

Eligibility Criteria

Inclusion Criteria

  • Diagnosed with cerebral palsy.
  • Spasticity in at least one of the lower extremity muscle groups.
  • No contraindications to shockwave therapy.
  • Applied Botulinum Toxin Type A injection for at least one spastic muscle of lower extremity.
  • Agreed to participate to study (patient/primary caregiver)

Exclusion Criteria

  • Surgery history within the last year of the muscle to be injected and treated
  • Having uncontrolled epilepsy.
  • Having infection
  • Coagulopathy

Outcomes

Primary Outcomes

Modified Aschworth Scale

Time Frame: 3 months (before injection, first week, first month and third month after injection.)

Scoring system used to evaluate spasticity. Spasticity scored as 0, 1, 1+, 2, 3, 4.

Modified Tradiue Scale

Time Frame: 3 months (before injection, first week, first month and third month after injection.)

Scoring system used to evaluate spasticity. Spasticity scored as 0,1,2,3,4.

Modified Timed Up and Go Test

Time Frame: 3 months (before injection, first week, first month and third month after injection.

The test for evaluate the functionality of pediatric patients with cerebral palsy. Only one chair and a surface for the patient to walk three meters are required. The time it takes for the patient to get up from the chair, walk the specified distance and sit back in the chair is recorded.

Facies Pain Scale Revised

Time Frame: 3 months (before injection, first week, first month and third month after injection.)

The scale for evaluate the pain level of pediatric patients. Chosen faces are scored 0, 2, 4, 6, 8, or 10, counting left to right, so "0" equals "No pain" and "10" equals "Very much pain."

Passive Range of Motion

Time Frame: 3 months (before injection, first week, first month and third month after injection.)

Goniometric measurement of the range of motion of the joint of the injected muscle

Goal Attaintment Scale

Time Frame: 3 months (before injection, first week, first month and third month after injection.)

The method of scoring the extent to which patient's individual goals are achieved in the course of intervention. GAS comprises of goals divided into a 5-point scale from -2 to +2. Achievement of goal = 0 Achieved somewhat more than expected outcome = +1 Achievement of much more than expected goal = +2 Achievement of somewhat less than expected goal = -1 Achievement of much less than expected goal = -2

Study Sites (1)

Loading locations...

Similar Trials