EUCTR2008-004099-26-DKActive, not recruitingPhase 1
Randomised trial on combined effects of dual blockade of the renin angiotensin system and phosphate binding in diabetic and non-diabetic patients with impaired renal function. - DUAL study
Departmnet of nephrology0 sitesStarted: July 22, 2009Last updated:
Conditions
Drugs
Trial Snapshot
- Phase
- Phase 1
- Status
- Active, not recruiting
- Sponsor
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional clinical trial of medicinal product
Eligibility Criteria
- Sex
- All
Inclusion Criteria
- •Cr EDTA clearence 25-70 ml/min
- •proteinuria > 0,5 g/day
- •s-potassium < 6mmol/l
- •signed informed consent
- •life expectancy > 2 years
- •CRP, fibrinogen, LDH, ALAT, bilirubin below 2 times upper normal range (reference values)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range
Exclusion Criteria
- •former dialysis og transplanted patient
- •uncontrolled hypertension
- •arythmia or ischemic heart disease
- •chronic infection
- •pregnancy or no use of safe anticonception
- •diabtes with HbA1c>10%
- •immunosuppressiv therapy
- •chronic cough
- •allergy to any of the used study medications
- •proteinuria>10g/day
- •obstructive urinary tract disease
- •ionized s-calcium > 1,4 mmol/l or s-phosphate < 0,8,mmol/l
- •participation inother interventional studies
Investigators
Similar Trials
Completed
Not Applicable
A study on which kind of hemostatic sponges has a more effective hemostatic effect for patients taking posterior spinal fusion surgeriesSpinal surgerySurgeryISRCTN29254316Peking Union Medical College Hospital50
Completed
Not Applicable
A randomized controlled trial of the effects of different levels of graded support on symptoms of anxiety and depression in adults using the Internet-based Wellbeing CourseMajor depressive disorder (a depressive disorder)Generalised anxiety disorder (an anxiety disorder)Panic disorder (with or without agoraphobia) (both anxiety disorders)Social phobia (an anxiety disorder)Mental Health - DepressionMental Health - AnxietyACTRN12610001058066Centre for Emotional Health, Department of Psychology, Macquarie University250
Recruiting
Not Applicable
A comparative study on steroid therapy in children with nephrotic syndromeephrotic syndromeSLCTR/2016/027niversity Renal Clinic64
Not yet recruiting
Phase 4
Comparison of two tapering regimens in the management of glucocorticoid withdrawal - the PRED-STOP trialglucocorticoid-responsive dermatological conditionspituitary-adrenal axis suppressionMetabolic and Endocrine - Other metabolic disordersInflammatory and Immune System - Other inflammatory or immune system disordersRespiratory - AsthmaSkin - Dermatological conditionspolymyalgia rheumaticaasthmarheumatoid arthritisACTRN12621000614897A/Prof W Inder - Investigator initiated120
Completed
Phase 3
Bi-level Ventilatory Support during exacerbations of Cystic FibrosisHuman Genetics and Inherited Disorders - Cystic fibrosisCystic FibrosisACTRN12605000437662SWSAHS40