Oxygen Insuflation and ArterialDesaturation During Tracheal Intubation in Children
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Infants
- Sponsor
- Medical University of Vienna
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- time to oxygen saturation
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
Infants (0-1 yr.) with anticipated difficult airways will be enrolled in the study. Specifically, we will include infants with cleft palate, Pierre Robin, Treacher Collins, trisomy 21, or similar congenital malformations. Patients with American Society of Anesthesiologists physical status scores ≥3 will be excluded, as will those with congenital heart disease and left-to-right shunting. Patients will be randomly assigned to laryngoscopy with or without simultaneous insufflation of oxygen at 4 L/minute. Oxygen will be provided by a flowmeter connected via rigid tubing to the track-mounted endotracheal tube on the AirTraq. Randomization (1:1) will be based on computer-generated codes with random block sizes and stratified by hospital; allocation will be concealed and provided to clinicians via a secure web site that will be accessed shortly before induction of anesthesia.
Investigators
Olga Plattner
M.D.
Medical University of Vienna
Eligibility Criteria
Inclusion Criteria
- •infants (0-2) difficult airways
Exclusion Criteria
- •. Patients with American Society of Anesthesiologists physical status scores ≥3 congenital heart disease left-to-right shunting
Outcomes
Primary Outcomes
time to oxygen saturation
Time Frame: Day 1
The randomized groups will be compared on time between laryngoscope (airtraq) insertion and reaching an oxygen saturation of 90%using a 2-tailed t-test or Wilcoxon-Mann-Whitney test, as appropriate.
Secondary Outcomes
- mean oxygenation comparison(Day 1)