Work of Breathing in Premature Infants at Discharge
- Conditions
- Bronchopulmonary DysplasiaVery Low Birth Weight InfantPrematurity
- Registration Number
- NCT03682575
- Lead Sponsor
- Christiana Care Health Services
- Brief Summary
The purpose of this study is to compare how premature infants who required oxygen for at least 28 days during their time in the NICU (Neonatal Intensive Care Unit) breathe at discharge compared to premature infants who did not require oxygen for at least 28 days during their time in the NICU.
- Detailed Description
Work of breathing tests will be performed on premature infants who required oxygen for at least 28 days during their time in NICU. These same work of breathing tests will be performed in another group of premature infants who did not require oxygen for at least 28 days during their time in the NICU. The two groups will be compared.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 78
- Infants born at greater than 26 weeks gestation, weighing less than 1500 grams at birth.
- Infants with diagnosis of BPD and without diagnosis of BPD
- Infants with skeletal, neuromuscular, or abdominal surgical disorders that affect the accuracy of work of breathing measurements will be excluded.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Work of breathing indices 25 minutes Respiratory Inductance Plethysmography (RIP) measurements will be taken and Phase Angle will be measured.
- Secondary Outcome Measures
Name Time Method Intermittent Hypoxia 25 minutes Oxygen saturation will be measured using a high resolution pulse oximeter.
Trial Locations
- Locations (1)
Christiana Care Health Services, Inc
🇺🇸Newark, Delaware, United States
Christiana Care Health Services, Inc🇺🇸Newark, Delaware, United States