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临床试验/NCT04178837
NCT04178837Unknown不适用

Role of Ultrasound Imaging in Diagnosis of Juvenile Idiopathic Arthritis

Assiut University0 个研究点目标入组 33 人开始时间: 2020年2月24日最近更新:
适应症

试验速览

阶段
不适用
入组人数
33
主要终点
Role of Ultrasound imaging in diagnosis of juvenile idiopathic arthritis

研究概览

简要总结

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood and an important cause of acquired disability in children . Despite the heterogeneity, all forms of JIA are characterized by prolonged synovial inflammation that can cause cartilage and bone damage, with severe impairment of physical function and impact on the quality of life. The presence of joint involvement in JIA may be expressed by ultrasonography findings such as synovial proliferation, effusion, cartilage thinning and bone erosions. US has demonstrated higher sensitivity in detecting synovitis compared to clinical examination MSUS is commonly regarded as a very useful tool in children, as outlined by the results of recent national and international surveys among pediatric rheumatologists .For most of the respondents, MSUS owned particular relevance for the ability to detect subclinical synovitis and to improve the classification of patients in JIA subtypes, as guidance to intraarticular corticosteroid injections and for capturing early articular damage. In addition, some specific joints were considered as most suited to be studied by MSUS, specifically the midfoot, the ankle, the hip, the wrist, the small joints of hands and feet. .

详细描述

Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood and an important cause of acquired disability in children . Despite the heterogeneity, all forms of JIA are characterized by prolonged synovial inflammation that can cause cartilage and bone damage, with severe impairment of physical function and impact on the quality of life. The presence of joint involvement in JIA may be expressed by ultrasonography findings such as synovial proliferation, effusion, cartilage thinning and bone erosions. US has demonstrated higher sensitivity in detecting synovitis compared to clinical examination MSUS is commonly regarded as a very useful tool in children, as outlined by the results of recent national and international surveys among pediatric rheumatologists .For most of the respondents, MSUS owned particular relevance for the ability to detect subclinical synovitis and to improve the classification of patients in JIA subtypes, as guidance to intraarticular corticosteroid injections and for capturing early articular damage. In addition, some specific joints were considered as most suited to be studied by MSUS, specifically the midfoot, the ankle, the hip, the wrist, the small joints of hands and feet. .

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
1 Year 至 17 Years(Child)
性别
All
接受健康志愿者

入选标准

  • Age between 1-17 years only.
  • Both sexes.
  • children with any type of Juvenile Idiopathic Arthritis
  • Exclusion criteria
  • Age above 17years.
  • Children with arthritis of known cause.

排除标准

  • 未提供

结局指标

主要结局

Role of Ultrasound imaging in diagnosis of juvenile idiopathic arthritis

时间窗: 2019_2021

Role of Ultrasound imaging in diagnosis activity \&exacepation of juvenile idiopathic arthritis

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Hossam eldeen Esmael Zayan

asmaa mohammed abd elhameed ali (amaeali)

Assiut University

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