Role of Ultrasound Imaging in Diagnosis of Juvenile Idiopathic Arthritis
试验速览
- 阶段
- 不适用
- 入组人数
- 33
- 主要终点
- Role of Ultrasound imaging in diagnosis of juvenile idiopathic arthritis
研究概览
简要总结
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood and an important cause of acquired disability in children . Despite the heterogeneity, all forms of JIA are characterized by prolonged synovial inflammation that can cause cartilage and bone damage, with severe impairment of physical function and impact on the quality of life. The presence of joint involvement in JIA may be expressed by ultrasonography findings such as synovial proliferation, effusion, cartilage thinning and bone erosions. US has demonstrated higher sensitivity in detecting synovitis compared to clinical examination MSUS is commonly regarded as a very useful tool in children, as outlined by the results of recent national and international surveys among pediatric rheumatologists .For most of the respondents, MSUS owned particular relevance for the ability to detect subclinical synovitis and to improve the classification of patients in JIA subtypes, as guidance to intraarticular corticosteroid injections and for capturing early articular damage. In addition, some specific joints were considered as most suited to be studied by MSUS, specifically the midfoot, the ankle, the hip, the wrist, the small joints of hands and feet. .
详细描述
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood and an important cause of acquired disability in children . Despite the heterogeneity, all forms of JIA are characterized by prolonged synovial inflammation that can cause cartilage and bone damage, with severe impairment of physical function and impact on the quality of life. The presence of joint involvement in JIA may be expressed by ultrasonography findings such as synovial proliferation, effusion, cartilage thinning and bone erosions. US has demonstrated higher sensitivity in detecting synovitis compared to clinical examination MSUS is commonly regarded as a very useful tool in children, as outlined by the results of recent national and international surveys among pediatric rheumatologists .For most of the respondents, MSUS owned particular relevance for the ability to detect subclinical synovitis and to improve the classification of patients in JIA subtypes, as guidance to intraarticular corticosteroid injections and for capturing early articular damage. In addition, some specific joints were considered as most suited to be studied by MSUS, specifically the midfoot, the ankle, the hip, the wrist, the small joints of hands and feet. .
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 1 Year 至 17 Years(Child)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between 1-17 years only.
- •Both sexes.
- •children with any type of Juvenile Idiopathic Arthritis
- •Exclusion criteria
- •Age above 17years.
- •Children with arthritis of known cause.
排除标准
- 未提供
结局指标
主要结局
Role of Ultrasound imaging in diagnosis of juvenile idiopathic arthritis
时间窗: 2019_2021
Role of Ultrasound imaging in diagnosis activity \&exacepation of juvenile idiopathic arthritis
次要结局
未报告次要终点
研究者
Hossam eldeen Esmael Zayan
asmaa mohammed abd elhameed ali (amaeali)
Assiut University
