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临床试验/CTRI/2026/03/106021
CTRI/2026/03/106021尚未招募不适用

Association of muscle ultrasound with weaning outcomes in mechanically ventilated critically ill patients : influence of high vs low mNUTRIC score.

DR HARSH RATHORE1 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2026年3月23日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
70
试验地点
1

研究概览

简要总结

This study aims to investigate the predictive value of serial muscle ultrasound measurements [diaphragm excursion (DE), diaphragm thickening fraction (DTF), and rectus femoris cross-sectional area (RFCSA)] for weaning outcomes in mechanically ventilated critically ill patients, and to determine whether the mNUTRIC score (high vs low) influences the relationship between muscle ultrasound findings and weaning success.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 99.00 Year(s)(—)
性别
All

入选标准

  • Age more than 18 years
  • Patients requiring invasive mechanical ventilation within 24 hours of ICU admission
  • Expected duration of mechanical ventilation more than 48 hours (as assessed by the treating intensivist)
  • Ability to obtain informed consent from the patient or legally acceptable representative.

排除标准

  • Patients with pre-existing neuromuscular disorders.
  • Patients with known diaphragmatic pathology (diaphragmatic paralysis, eventration, or prior phrenic nerve injury)
  • Patients with spinal cord injury at the cervical or high thoracic level
  • Patients with previous lower limb amputation or pathology preventing RFCSA measurement
  • Morbid obesity (BMI more than 40), limiting adequate ultrasound visualization
  • Presence of chest tubes, surgical dressings, or wounds preventing ultrasound probe placement
  • Pregnancy
  • Patients who are readmitted to the ICU after previous enrolment in the study
  • Refusal of consent by patient or legally acceptable representative
  • Patients who are expected to be transferred to another facility within 5 days.

研究者

发起方
DR HARSH RATHORE
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

HARSH RATHORE

Amrita institute of medical sciences, Faridabad

研究点 (1)

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