跳至主要内容
临床试验/CTRI/2024/08/071806
CTRI/2024/08/071806尚未招募不适用

Evaluation of Diaphragmatic thickness fraction by Ultrasonography as a predictor for successful weaning from mechanical ventilation in ICU patients.

All India Institute of Medical Sciences Patna1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2024年8月11日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
To determine the sensitivity and specificity of Diaphragmatic Thickening Fraction (DTF) as a predictor for successful weaning in ICU patients.

研究概览

简要总结

One of the commonest causes of difficult weaning has been diaphragmatic dysfunction, which progressively worsens while using mechanical ventilation. USG examination allows the direct visualization of the diaphragm thickness during active breathing & reflect the magnitude of diaphragmatic effort. Ultrasound is safe, non-invasive, without radiation hazards, and available at the bedside modality for assessment of lung and diaphragm for weaning of ICU patients. The study expects to evaluate diaphragmatic thickness fraction (DTF) assessed by ultrasonography as predictor during weaning from mechanical ventilation. This may provide a novel, non-invasive approach to predict successful extubation, potentially reducing reintubation rates and guiding personalized weaning strategies in critical care settings, thereby enhancing patient outcomes and optimizing resource utilization.

研究设计

研究类型
Observational

入排标准

年龄范围
18.00 Year(s) 至 65.00 Year(s)(—)
性别
All

入选标准

  • Age 18 to 65 years.
  • Mechanical ventilation for minimum 12 hours and maximum 7 days.
  • Intubated and mechanically ventilated patient ready to be weaned.

排除标准

  • Patients with history of neuromuscular disease Patients with history suggestive of diaphragmatic dysfunction Patients with chest tube in situ Pregnant Patients Tracheostomized patients.

结局指标

主要结局

To determine the sensitivity and specificity of Diaphragmatic Thickening Fraction (DTF) as a predictor for successful weaning in ICU patients.

时间窗: RSBI assessed 60 min after successful Spontaneous Breathing trial. | ABG done at 1 hour and 6 hapur after extubation.

次要结局

  • Not applicable(Not applicable)

研究者

发起方
All India Institute of Medical Sciences Patna
申办方类型
Government medical college
责任方
Principal Investigator
主要研究者

Dr Muskan Dogney

All India Institute of Medical sciences, Patna

研究点 (1)

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