Identification of effective weaning through diaphragmatic ultrasound added to clinical parameters among mechanically ventilated patients in ICU at tertiary care centre: A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Diaphragmatic thickness fraction.
研究概览
简要总结
Ultrasonography provides simplenon invasive method of quantifying diaphragmatic movements. Imaging diaphragmwith ultrasound can be done by measuring diaphragm thickening fraction (DTF). Diaphragmatic parameters determined by bedside ultrasonography can predictweaning outcome with better performance than conventional parameters. The primary objective is to determine the diagnostic accuracyof diaphragm thickening fraction (DTF) in predicting weaning success. After spontaneous breathing trial, rapid shallowbreathing index (RSBI) will be calculated. The thickness of the diaphragm at maximuminspiration (TDmax) and maximum expiration (TDmin) willmeasured as the Diaphragm Thickening Fraction (DTF).
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients who are healthy before the disease onset who are mechanically ventilated for more than 72 hours and with satisfactory clinical weaning parameters and have readiness for weaning from mechanical ventilation.
排除标准
- •Patients with neuromuscular disorders.
- •Patients with pre existing diaphragmatic palsy.
- •Tracheostomised patients.
- •Patients with pneumothorax.
- •Poor image quality of ultrasound.
结局指标
主要结局
Diaphragmatic thickness fraction.
时间窗: From 72 hours after intubation till extubation from mechanical ventilation.
次要结局
- Rapid shallow breathing index.(After spontaneous breathing trial till extubation from mechanical ventilation.)