Phase 2 study of S-1 for elderly patients with advanced non-small cell lung cancer
Phase 2
- Conditions
- non-small cell lung cancer
- Registration Number
- JPRN-UMIN000006527
- Lead Sponsor
- Kitasato University School of Medicine Department of Respiratory Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 35
Inclusion Criteria
Not provided
Exclusion Criteria
1)Active lung disease such as interstitial pneumonia or pulmonary fibrosis. 2)Uncontrollable pleural or pericardial effusion or ascites. 3)Simultaneous or metachronous double cancers. 4)Severe complications. 5)Symptomatic brain metastases. 6)The case suspected of infection with feaver. 7)Mental disease or psychotic manifestation. 8)A history of serious drug allergy. 9)A history of sever allergic reaction with S-1 10)A history of adjuvant chemotherapy including S-1. 11)Being treated with other pyrimidine fluoride antineoplastic agents. 12)Being treated with flucytosine. 13)Any patients judged by the investigator to be unfit to participate in the study.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Response rate
- Secondary Outcome Measures
Name Time Method Progression-free survival, Overall survival, Safety, To explore EGFR status and K-ras status related to the effect.