Effect of Ganglionar Transcutaneous Electrical Nerve Stimulation on Central Arterial Pressure in Healthy Young Population
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 30
- Locations
- 2
- Primary Endpoint
- tonometry
Study Overview
Brief Summary
This study will evaluate the applications of ganglionar electrical stimulation in patients with Chagas Disease and Ischemic Heart Failure patients.
Detailed Description
A Crossover Randomized Controlled Study will be developed with 3 groups: Healthy Older, Ischemic Heart Failure and Chagas Disease. This individuals will be randomized in two groups: TENS and placebo (same stimulus without electrical output) with 48 hrs between the interventions.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Supportive Care
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 40 Years to 70 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Ischemic and Chagas disease previously diagnosticated
- •Age above 40 years old
Exclusion Criteria
- •No vascular disease
- •No recent surgery
- •No recent infections
Outcomes
Primary Outcomes
tonometry
Time Frame: participants will be followed for the duration of myostimulation protocol, an expected average of 5 weeks
Applanation tonometry (AT) accurately reflects arterial stiffness method and has demonstrated a strong correlation with ventricular-vascular coupling. Increased arterial stiffness and wave reflection have also been reported in patients with systolic and diastolic HF.
Secondary Outcomes
- Cardiorespiratory Evaluation(participants will be followed for the duration of myostimulation protocol, an expected average of 5 weeks)
Investigators
Gerson Cipriano Jr
PhD
University of Brasilia