临床试验/CTRI/2023/03/050390

CTRI/2023/03/050390尚未招募不适用

The Effect of Preoperative IV Tranexamic acid on intraoperative blood loss in cancer surgeries at a tertiary care centre in South India â€“ A Randomised Controlled Trial

未提供1 个研究点分布在 1 个国家目标入组 120 人开始时间: 2023年8月3日最近更新: 2023年2月3日

试验速览

阶段: 不适用
状态: 尚未招募
入组人数: 120
试验地点: 1
主要终点: 1. Operative blood loss

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

To determine the impact of preoperative administration of tranexamic acid on

1. Intra-operative blood loss and

2. transfusion rates

in major oncological surgeries

研究设计

研究类型: Interventional
分配方式: Stratified block randomization
盲法: Participant and Investigator Blinded

入排标准

年龄范围: 10.00 Year(s) 至 80.00 Year(s)（—）
性别: All

入选标准

•all cancer patients undergoing surgeries for breast gyanecology, Head &neck ,GI, soft tissue sarcoma& others.

排除标准

•Patients with coagulopathy(activated partial thromboplastin time >50 s or International normalised ratio >1.5, platelets <50 X 109/L), Recent history of acetylsalicylic acid ingestion (< 5 days), Patients on anticoagulation therapy (received heparin within 4 hours or received warfarin 3 days preoperatively), Those with known peripheral vascular disease, Pre-existing renal dysfunction (serum creatinine >1.2 mg/dl), Liver dysfunction, Known allergy to tranexamic acid.

结局指标

主要结局

1. Operative blood loss

时间窗: baseline

2. Blood transfusion rates

时间窗: baseline

次要结局

1.Length of hospital stay(2.Length of stay in ICU)

研究者

发起方

未提供

研究点 (1)

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