Effect of a tomato sauce (OsteoCol) from vine-ripened tomatoes on lipids

Not Applicable

Completed

• Conditions: Polygenic hypercholesterolemia; Nutritional, Metabolic, Endocrine

• Registration Number: ISRCTN13244115
• Lead Sponsor: niversity Magna Grecia Catanzaro

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/33407609/ (added 12/01/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-16
• Study Completion: 2020-05-30
• Last Update Posted: 25 January 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 108

Inclusion Criteria

1. Individuals with polygenic hypercholesterolemia
2. Both genders
3. Aged over 40 years
4. Not taking medications or supplements

Exclusion Criteria

1. Familial hypercholesterolemia
2. Triglycerides concentration over 200 mg/dl
3. Secondary causes of hyperlipidemia
4. Debilitating diseases, as ascertained

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> 1. Total cholesterol measured by chemiluminescent immunoassay on COBAS 8000 (Roche, Switzerland), according to the manufacturer’s instructions at baseline and 6 weeks<br> 2. LDL-cholesterol calculated by the Friedewald formula at baseline and 6 weeks<br>

Secondary Outcome Measures

Name	Time	Method
DL-cholesterol according with basal LDL-tertiles measured at baseline and 6 weeks