EFFECT OF A SINGLE INTRAOPERATIVE DOSE OF DEXAMETHASONE ON GLYCEMIC PROFILE IN POST OPERATIVE PATIENTS, UNDERGOING ELECTIVE LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA: RANDOMISED CONTROLLED TRIAL
Trial Snapshot
- Phase
- Phase 3 4
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 100
- Locations
- 1
- Primary Endpoint
- To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
Study Overview
Brief Summary
This study will be conducted in the department of Anaesthesiology, Dr. S. N. MEDICAL COLLEGE and associated group of hospitals on patients posted for laparoscopic surgery . The aim is to study the effect of a single dose of dexamethasone on glycemic profile up to 72hours in postoperative patients undergoing elective laparoscopic surgery under general anaesthesia and also to compare the incidence of postoperative nausea and vomiting (PONV) and Postoperative pain in term of VAS score.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Investigator Blinded
Eligibility Criteria
- Ages
- 18.00 Year(s) to 70.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •The patients of aged 18-70 years with Body Mass Index (BMI) ranging from 18.5 to 24.9 kg/m2, American Society of Anesthesiologists (ASA) physical status I and non-diabetic ASA II status posted for elective laparoscopic surgery will be recruited and studied for 72 hours.
Exclusion Criteria
- •Candidates with preexisting diabetes mellitus (FBS more than 126 mg/dl, postprandial blood sugar (PPBS) more than 200 mg/dl, HbA1c more than 6.5), Chronic steroid therapy (taking steroid more than 10mg, for more than 10 days within last 10 months), History of allergy to dexamethasone, Pregnancy, History of peptic ulcer disease, Malignancy, Duration of anaesthesia more than 2 hours, Patients who have history of any vomiting, Retching, or nausea in the 24 hours preceding the administration of anaesthesia.
Outcomes
Primary Outcomes
To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
Time Frame: To compare the changes in the glycemic profile up to 72hours in patients receiving a single dose of dexamethasone in elective laparoscopic surgery
Secondary Outcomes
- To compare the incidence of postoperative nausea and vomiting (PONV)(And Postoperative pain in term of VAS score.)
Investigators
jyoti
Dr SN Medical College, Jodhpur , Rajasthan