Comparison of the effect of intravenous dexmedetomidine and ketamine on postoperative analgesia in lower limb fracture surgeries under subarachnoid block
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 50
- 试验地点
- 1
- 主要终点
- To compare postoperative analgesia in terms of duration of analgesia, total rescue
研究概览
简要总结
Following approval from the Institutional Research and Ethics Committee, the study will be conducted at our institution involving patients scheduled for lower limb fracture surgeries under subarachnoid block. A comprehensive pre-anaesthetic evaluation will be performed, and the study protocol will be thoroughly explained to each patient. Individuals who meet the inclusion criteria and provide informed consent will be enrolled in the study.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •1.Patients posted for lower limb fracture surgeries 2.ASA PS I and II.
排除标准
- •1.Patients allergic to dexmedetomidine or ketamine 2.Patients with ischemic heart disease, severe renal and liver impairment 3.Patients on beta blockers 4.Duration of surgery more than 120 minutes.
结局指标
主要结局
To compare postoperative analgesia in terms of duration of analgesia, total rescue
时间窗: Postoperative analgesia will be evaluated by Numerical rating scale at 0,1,2,4,6,12 & 24 hours from stopping infusion of study drug.
analgesia and NRS pain scores
时间窗: Postoperative analgesia will be evaluated by Numerical rating scale at 0,1,2,4,6,12 & 24 hours from stopping infusion of study drug.
次要结局
- To compare intraoperative & postoperative sedation scores
- To assess side effects like hemodynamic instability(Hemodynamics will be monitored every 5 minutes intraoperatively.)
研究者
MEGHNA R NAMBIAR
Government medical college, Kozhikode