TO STUDY THE EFFECT OF MAGNESIUM SULPHATE NEBULISATION IN PREVENTION OF POST-OPERATIVE SORE THROAT FOLLOWING I-GEL INSERTION FOR GENERAL ANAESTHESIA
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 48
- Locations
- 1
- Primary Endpoint
- To study the efficacy of Magnesium sulphate nebulization in prevention of post operative sore throat following use of I-gel.
Study Overview
Brief Summary
Post operative sore throat is a common complaint in patients receiving general anaesthesia to undergo surgical procedures over the years.
Irritation and inflammation of the airway is considered the most common cause of post operative sore throat.
Magnesium sulphate is a NMDA antagonist with anti inflammatory property which work on peripheral nerve endings in pharyngeal mucosa and can reduce the incidence of post operative sore throat.
This study is intended to evaluate and assess the incidence and severity of post operative sore throat following administration of magnesium sulphate to the patients 15 minutes pre-operatively.
Incidence and severity of post operative sore throat will be graded on verbal rating scale post operatively along with assessment of any undesirable side effects following usage of supraglottic airway device I-gel to maintain anaesthesia.
Study Design
- Study Type
- Interventional
- Allocation
- Not Applicable
- Masking
- Not Applicable
Eligibility Criteria
- Ages
- 20.00 Year(s) to 60.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Patients posted for elective surgeries and with ASA PS class 1 and 2.
Exclusion Criteria
- •patient refusal, Patient with history of frequent sore throat and asthma, Oral surgeries, chronic obstructive pulmonary disease, head and neck surgeries, Mallampatti grade 3 and above, Known allergies to study drug, Recent non- steriodal anti-inflammatory drugs NSAID medication those who received.
Outcomes
Primary Outcomes
To study the efficacy of Magnesium sulphate nebulization in prevention of post operative sore throat following use of I-gel.
Time Frame: 24 hours post operative.
Secondary Outcomes
- To assess the severity of hemodynamic variability (blood pressure and pulse rate)(perioperatively)