Airway Responsiveness and Inflammation in Adolescent Elite Swimmers: a 3-Year Prospective Follow-up Study
试验速览
- 阶段
- 不适用
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Airway responsiveness to eucapnic voluntary hyperpnea and methacholine
研究概览
简要总结
Previously the investigators have found that adolescent elite swimmers, who have been involved in competitive swimming for only a few years, have not developed respiratory symptoms, signs of airway inflammation or airway hyperresponsiveness exept for a slight increase in airway responsiveness to eucapnic voluntary hyperpnea. In the current study, the investigators will be doing a 3-year follow-up study on the swimmers studied previously.
详细描述
Even though studies suggest that elite sport can cause AHR and airway inflammation, more studies are needed to elucidate how and when AHR and airway inflammation develop; and there is a lack of follow-up studies. The present study will give us a chance to do a follow-up study to register changes in AHR and airway inflammation in athletes without any significant airway changes at baseline.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 19 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age 15-19 years
- •Part of the Danish National Swimming Association's talent program for young swimmers at the baseline study
- •Informed consent
排除标准
- •Upper respiratory tract infection in the previous 4 weeks (visits will be postponed)
结局指标
主要结局
Airway responsiveness to eucapnic voluntary hyperpnea and methacholine
时间窗: Three years
次要结局
- Airway inflammation(Three years)