ACTRN12623000285651招募中未知
A pilot study designed to compare differences in stimulus evoked electroencephalographic variability between participants assessed to be cognitively normal and participants diagnosed with mild dementia
St Vincent's Hospital Melbourne0 个研究点目标入组 48 人开始时间: 2023年3月16日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
- 入组人数
- 48
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 60 Years 至 o limit（—）
- 性别
- All
入选标准
- •Male and female participants 60 years or older
- •English speaking and basic levels of literacy in order to be able to give informed consent and to follow all instructions
- •Normal or corrected hearing and vision
- •CN group: Formally assessed to be cognitively normal by CADMS Neuropsychiatrist
- •MDAD group: Formal diagnosis by CADMS Neuropsychiatrist of possible or probable Alzheimer's Disease; Mild dementia as defined by Clinical Dementia Rating score of 0.5 - 1, Global Deterioration Scale score of 4, and Min-mental Status Examination score of 18 - 23
排除标准
- •Colour blindness
- •Any history of illness affecting cognitive function e.g., vitamin B12 deficiency, hypothyroidism, significant psychiatric disorders (such as major depression or schizophrenia), neurodegenerative disorders, ischaemic stroke, epilepsy, brain tumour, significant head trauma
- •Any episodes of unexplained loss of consciousness
- •History of substance or alcohol abuse
- •Taking an acetylcholinesterase inhibitor, or any other agent demonstrated to affect cognitive function, within the last 3 months
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