ACTRN12623000285651
Recruiting
未知
A pilot study designed to compare differences in stimulus evoked electroencephalographic variability between participants assessed to be cognitively normal and participants diagnosed with mild dementia
St Vincent's Hospital Melbourne0 sites48 target enrollmentMarch 16, 2023
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Dementia
- Sponsor
- St Vincent's Hospital Melbourne
- Enrollment
- 48
- Status
- Recruiting
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Male and female participants 60 years or older
- •English speaking and basic levels of literacy in order to be able to give informed consent and to follow all instructions
- •Normal or corrected hearing and vision
- •CN group: Formally assessed to be cognitively normal by CADMS Neuropsychiatrist
- •MDAD group: Formal diagnosis by CADMS Neuropsychiatrist of possible or probable Alzheimer's Disease; Mild dementia as defined by Clinical Dementia Rating score of 0\.5 \- 1, Global Deterioration Scale score of 4, and Min\-mental Status Examination score of 18 \- 23
Exclusion Criteria
- •Colour blindness
- •Any history of illness affecting cognitive function e.g., vitamin B12 deficiency, hypothyroidism, significant psychiatric disorders (such as major depression or schizophrenia), neurodegenerative disorders, ischaemic stroke, epilepsy, brain tumour, significant head trauma
- •Any episodes of unexplained loss of consciousness
- •History of substance or alcohol abuse
- •Taking an acetylcholinesterase inhibitor, or any other agent demonstrated to affect cognitive function, within the last 3 months
Outcomes
Primary Outcomes
Not specified
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