Effects of physical exercise under different levels of effort to prevent atherosclerosis and risk factors in elderly wome

Phase 2

• Conditions: Physical exercise; risk factors; atherosclerosis; G11.427.410.698.277; E05.318.740.600.800.725; C14.907.137.126.307

• Registration Number: RBR-82chym
• Lead Sponsor: niversidade Federal de Goiás

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-06-03
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruitment completed
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

60 years old and 79 years old; signature of the TCLE (according to resolution 466/2012); possibility of regular attendance; sedentary; not be diabetic; without limitations and / or motor disability of any kind.

Exclusion Criteria

Body mass index between 24 Kg / m2 and 40 Kg / m2; abdominal circumference greater than 80 cm; estimate of the metabolic equivalent (MET) below 4.5 METS or above 7.5 METS (<15.75 or> 26.25 ml / kg / min of Maximum Oxygen Volume).

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
It is expected to find positive endothelial modulation through physical exercise, exhibiting a reduction in the intimal average thickening and blood flow speed and / or an increase in the diameter of the common and internal carotid artery lumen after the intervention through physical exercise, verified by arterial ultrasonography and analyzedby comparisons between groups using Student's t test and Tukey's test.<br>The data will be analyzed using the Statistical Packge Social Science software, version 23 (SPSS-v.23). The level of significance considered will be 5%.

Secondary Outcome Measures

Name	Time	Method
<br>It is expected that the study will result in the reduction of cardiovascular risk factors, in addition to increasing physical and motor parameters of the participants, being investigated by anthropometric measurements, measurement of brachial and ankle blood pressure, using a semi-automatic sphygmomanometer, blood collections for biochemical analyzes, tetrapolar bioimpedance and ergospirometric testing. The analyzes will be by comparisons between groups using Student's t test and Tukey's test.<br>The data will be analyzed using the Statistical Packge Social Science software, version 23 (SPSS-v.23). The level of significance considered will be 5%.