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Clinical Trials/NCT06334328
NCT06334328
Completed
Not Applicable

Feasibility and Acceptability of Virtual Reality-based Mindful Movement Therapy for Older Adults

Drexel University1 site in 1 country12 target enrollmentAugust 15, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Cognitive Decline
Sponsor
Drexel University
Enrollment
12
Locations
1
Primary Endpoint
Treatment acceptability
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

The current proposal aims to 1) develop a technical platform and implementation plan for the delivery of a virtual reality-based mindful movement therapy (VR-MMT) protocol for older adults; and 2) conduct a clinical trial to examine the feasibility and preliminary efficacy of an 8-week, 16-session module VR-MMT intervention for this population. The findings of this study will help us to identify engagement barriers and refine the intervention contents as well as the study protocol necessary for the preparation of grant applications to conduct a controlled clinical trial. This study is innovative and high impact as this is the first study to examine the feasibility and preliminary efficacy of a VR-MMT intervention that could potentially ameliorate cognitive and mobility decline and promote psychological wellbeing in older adults by combining a widely accessible technology and creative embodiment-based approach.

Detailed Description

Age-related cognitive decline is a significant public health issue. Despite the benefit of regular physical activity in preserving cognitive function and overall health and wellbeing, approximately 30% of older adults are physically inactive due to a lack of motivation and other engagement barriers. Further, social isolation and loneliness are common in older adults which are associated with an increased risk of developing Alzheimer's disease (AD) and dementia. A combination of physical and cognitive training appears to be effective to improve cognitive function in older adults experiencing cognitive deterioration. Growing evidence suggests virtual reality(VR) is a promising tool to improve cognitive functioning in older adults. We have developed a novel virtual reality-based mindful movement therapy (VR-MMT) program for older adults that combines VR games, multisensory and cognitive stimulation, hand-eye and full body coordination, creative processes, expressive movement, mindfulness practice, and social connectedness. The current proposal aims to 1) develop a technical platform and implementation plan for the delivery of a VR-MMT protocol for older adults; and 2) conduct a clinical trial to examine the feasibility and preliminary efficacy of an 8-week, 16-session module VR-MMT intervention for this population. The findings of this study will help us to identify engagement barriers and refine the intervention contents as well as the study protocol necessary for the preparation of grant applications to conduct a controlled clinical trial. As this is the first study to examine the feasibility and preliminary efficacy of a VR-MMT intervention that could potentially ameliorate cognitive and mobility decline and promote psychological wellbeing in older adults by combining a widely accessible technology and creative embodiment-based approach, it meets the definition of "innovative, high impact" research. Our specific aims include: Aim 1: To develop (a) a technical platform and (b) an implementation plan for the delivery of a VR-MMT intervention for older adults. Technical development and implementation planning will be guided by the expert project team with key input from community stakeholders. Aim 2: To conduct a clinical feasibility trial to examine the safety, feasibility, and preliminary efficacy (primary outcomes: cognitive function, psychological wellbeing, physical activity participation, secondary outcomes: mobility performance, loneliness, self-efficacy) of an 8-week VR-MMT intervention for older adults.

Registry
clinicaltrials.gov
Start Date
August 15, 2022
End Date
January 31, 2024
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Minjung Shim, PhD

Assistant Professor

Drexel University

Eligibility Criteria

Inclusion Criteria

  • Subjects must be age 65 or older at the time of informed consent.
  • Able to move and stand without assistance
  • Subjects must be proficient in spoken and written English for consenting as well as for study participation
  • Subjects with medical conditions must be stable for these conditions. Stable control on medication is acceptable.
  • Subject must have normal visual acuity (or corrected to normal) and normal color vision as indicated by self-report.
  • Subject must have adequate hearing acuity as indicated by self-report.

Exclusion Criteria

  • Existing diagnosis of a neurodegenerative disorder (e.g., Alzheimer's Disease, Lewy Body Dementia, Frontal-Temporal Dementia).
  • Prior diagnosis that might impact cognition and movement abilities including: cardiovascular or respiratory illness or injury, substance abuse, schizophrenia, bipolar disorder, or other neurological diseases (e.g., epilepsy, Parkinson's disease, seizure disorder).
  • Affirmative answer to any Physical Activity Readiness Questionnaire for 70+ year-old adults (PAR-Q-70+) questionnaire.

Outcomes

Primary Outcomes

Treatment acceptability

Time Frame: Post intervention (Week 6)

Treatment Evaluation Inventory Short Form (post-intervention only) is a 9-item measure of the perceived acceptability of behavioral treatments. Items are rated on a 5-point scale with the anchor points 1 (strongly disagree) and 5 (strongly agree). Higher score meaning greater levels of treatment acceptability.

Treatment adherence

Time Frame: Throughout the intervention (week 1-week 6)

We will log participants' session attendance to track treatment adherence

Treatment satisfaction

Time Frame: Post intervention (Week 6)

Usefulness, Satisfaction, and Ease of Use Questionnaire (post-intervention only) is a 30-item instrument that examines four dimensions of usability: usefulness, ease of use, ease of learning, and satisfaction. Each question is rated on a seven-point scale with the anchor points 1 (strongly disagree) and 7 (strongly agree). There are also two open-ended response questions asking the user to list the most negative aspects and the most positive aspects. All items are summed to give a total score, with higher scores indicating greater usability.

Qualitative feedback

Time Frame: Post intervention (within 1-2 weeks after the conclusion of the 6-week intervention)

A semi-guided individual interview (30 min) will be conducted upon the completion of the intervention to learn about participants' experience of participating in the study, perceived benefits, perceived barriers, and suggestions for improvement.

Safety

Time Frame: Throughout the intervention (week 1-week 6)

We will log adverse event to assess safety of the intervention

Secondary Outcomes

  • The Warwick-Edinburgh Mental Well-being Scale (WEMWBS)(Pre and post intervention(Week 0 and Week 6))
  • Montreal Cognitive Assessment (MoCA)(Pre and post intervention (Week 0 and Week 6))
  • Physical Performance Battery (SPPB)(Pre and post intervention(Week 0 and Week 6))
  • Trail making test(Pre and post intervention(Week 0 and Week 6))
  • Physical Activity Scale for the Elderly (PASE)(Pre and post intervention(Week 0 and Week 6))
  • General Self-Efficacy Scale(Pre and post intervention(Week 0 and Week 6))
  • Positive Affect and Negative Affect Scale (PANAS)(Pre and post intervention(Week 0 and Week 6))

Study Sites (1)

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