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Clinical Trials/NCT04630184
NCT04630184
Recruiting
Not Applicable

Development and Impact of a Virtual Reality Exposure Intervention on Social Physical Anxiety During Physical Activity in Women With Obesity

Universite du Quebec en Outaouais1 site in 1 country45 target enrollmentSeptember 1, 2021

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Obesity
Sponsor
Universite du Quebec en Outaouais
Enrollment
45
Locations
1
Primary Endpoint
Acceptability of the protocol and the intervention
Status
Recruiting
Last Updated
3 years ago

Overview

Brief Summary

The objectives of the project are to: i) assess the feasibility and acceptability of the protocol and the VR exposure intervention in women with obesity, and ii) obtain an estimate of the effect of VR exposure intervention associated with an exercise training on SPA, compliance, adherence and persistence to the exercise training, as well as persistence in PA practice in the middle term to calculate the sample size for a future larger randomized controlled trial (RCT) in women with obesity.

A RCT of feasibility will be carried out. Forty-five women with obesity and a high level of SPA will be randomized into one of the following three groups: 1) Exercice and VR exposure (Ex + expo), 2) Exercise and psychological intervention control (Ex + control) or 3) waiting list (WL).

The interventions will have a physical exercise training (identical for all) and a psychology intervention (different according to the condition: VR exposure or control). The feasibility and acceptability of the protocol and the VR exposure intervention will be assessed at the end of the study. SPA, PA practice, anthropometry, internalization of weight bias, body appreciation, perceived pleasure, motivational regulation, self-efficacy, affects as well as perception effort will be evaluated with questionnaires and scales validated before and after the intervention and 6 months after the end of the intervention. Sociodemographic data, depressive symptoms, problematic eating behaviors and propensity to immersion will be assessed during the initial visit only. Adherence, adherence and persistence to the PA program will be calculated at the end of the intervention. Persistence in PA practice will be calculated using data collected immediately after the end of the intervention and 6 months after the intervention.

Detailed Description

Several studies show that a high level of social physical anxiety (SPA) can lead to avoidance and poor adherence to physical activity (PA) programs. Although this link is known and a high level of SPA is frequently found in women with obesity, no psychological intervention specific to the treatment of SPA has been developed to date. Exposure therapy is the treatment of choice for general social anxiety. However, this format of therapy can cause great discomfort for the patient and prevents complete control of the environment by the clinician. Virtual reality (VR), commonly employed in the treatment of anxiety disorders, offers a solution to these problems by allowing exposure to human stimuli in an adaptable environment and under the control of the clinician, with a reduction in stress patient discomfort. The objectives of the project are to: i) assess the feasibility and acceptability of the protocol and the VR exposure intervention in women with obesity, and ii) obtain an estimate of the effect of VR exposure intervention associated with an exercise training on SPA, compliance, adherence and persistence to the exercise training, as well as persistence in PA practice in the middle term to calculate the sample size for a future larger randomized controlled trial (RCT) in women with obesity. A RCT of feasibility will be carried out. Forty-five women with obesity and a high level of SPA will be randomized into one of the following three groups: 1) Exercice and VR exposure (Ex + expo), 2) Exercise and psychological intervention control (Ex + control) or 3) waiting list (WL). The interventions will have a physical exercise training (identical for all) and a psychology intervention (different according to the condition: VR exposure or control). The feasibility and acceptability of the protocol and the VR exposure intervention will be assessed at the end of the study. SPA, PA practice, anthropometry, internalization of weight bias, body appreciation, perceived pleasure, motivational regulation, self-efficacy, affects as well as perception effort will be evaluated with questionnaires and scales validated before and after the intervention and 6 months after the end of the intervention. Sociodemographic data, depressive symptoms, problematic eating behaviors and propensity to immersion will be assessed during the initial visit only. Adherence, adherence and persistence to the PA program will be calculated at the end of the intervention. Persistence in PA practice will be calculated using data collected immediately after the end of the intervention and 6 months after the intervention.

Registry
clinicaltrials.gov
Start Date
September 1, 2021
End Date
December 31, 2023
Last Updated
3 years ago
Study Type
Interventional
Study Design
Parallel
Sex
Female

Investigators

Sponsor
Universite du Quebec en Outaouais
Responsible Party
Principal Investigator
Principal Investigator

Aurelie Baillot

Professor

Universite du Quebec en Outaouais

Eligibility Criteria

Inclusion Criteria

  • inactive (\<150 min. of moderate to vigorous PA / week )
  • aged between 18 and 45 years
  • BMI ≥ 30 kg / m2
  • to be able to go to Université du Québec en Outaouais twice a week

Exclusion Criteria

  • to have a low to moderate social physical anxiety level (SPA score \<27/45 on the physical and social anxiety scale )
  • suffer from hypersensitivity to motion sickness
  • to be pregnant or plan to become over the next year
  • to take medication that may influence weight
  • to have undergone bariatric surgery
  • to have a contraindication to physical activity
  • to have participated in a physical activity program in the last 6 months supervised
  • to have an intellectual disability, and have a severe and persistent psychiatric problem (psychosis, bipolar disorder).

Outcomes

Primary Outcomes

Acceptability of the protocol and the intervention

Time Frame: At the end of the intervention (+ 12 weeks)

The acceptability of the protocol and the intervention will be qualitatively assessed through 5 to 7 semi-structured discussion groups by teleconference via the zoom platform. The participants will be interviewed for 75 minutes in sub-groups of 6 to 8 participants on their perception, opinion and experience regarding the intervention and the implementation of the protocol (barriers, facilitators, satisfaction, perceived benefits, recommendation and improvement). An interview guide constructed for the purpose of the study will ensure consistency of the themes explored between the different groups while guiding the group facilitation.

Feasibility of the protocol and the intervention

Time Frame: At the end of the study (+ 36 weeks)

The feasibility of the protocol will be assessed at the end of the study using the following criteria: i) the recruitment rate (number of participants recruited per month), ii) the retention rate (number of participants who have completed all the assessments and focus group and reason for dropout), iii) percentage of missing data (number of missing data out of number of total data) and iv) acceptance of randomization. The feasibility of the intervention will be evaluated at the end of the study using the following criteria: v) the participation rate (number of eligible participants who agreed to participate in the study), vi) the participation rate adherence (number of participants who completed the 8 psychological intervention sessions), vii) the attrition rate (number of participants who abandoned the psychological intervention and reasons). The achievement of the following criteria will be considered as a success factor in terms of feasibility (14, 23): i) recruitment rate ≤ 5.6,

Secondary Outcomes

  • Adherence to the physical activity (PA) intervention(At the end of the PA intervention (after 12 weeks))
  • Social physical anxiety change (0-12 weeks)(Before and after intervention (Baseline and after 12 weeks))
  • Compliance with the PA intervention(At the end of the PA intervention (after 12 weeks))
  • Physical activity change (0-12 weeks)(Before and after intervention (Baseline and after 12 weeks))
  • Persistance in the practice of PA after the intervention(Immediately after the intervention and at the end of the study (after 12 weeks and 36 weeks))

Study Sites (1)

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