The different intervention strategies to explore the objective evaluation of ''blood pathways blocked'' and ''qi pathways blocked'' of coronary atherosclerosis

Phase 1

• Conditions: Coronary atherosclerotic heart disease

• Registration Number: ITMCTR2000003592
• Lead Sponsor: Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. The patient meets the diagnostic criteria for coronary atherosclerotic heart disease, has a clear history of myocardial infarction, or coronary angiography or coronary CT confirmed coronary artery stenosis >=50%, and the severity of angina pectoris is I-II/I-III;
2. Those who meet the syndrome differentiation criteria of impassable qi and blood vessels in traditional Chinese medicine for coronary heart disease;
3. Aged 18 to 75 years old;
4. those who voluntarily sign written informed consent.

Exclusion Criteria

(1) Acute myocardial infarction combined with severe complications such as cardiogenic shock (cannot be corrected by conventional treatment), combined with mechanical complications;
(2) combined with other heart diseases or severe cardiac insufficiency (NYHA cardiac function classification> III);
(3) Acute coronary syndrome (ACS) patients with asymptomatic or stable symptoms;
(4) Patients with chronic kidney disease with severe heart, lung, liver and other vital organ dysfunction; severe primary diseases, such as hematopoiesis Systemic and/or severe heart, lung, liver and other vital organ dysfunction;
(5) recent cerebrovascular accidents, major operations and trauma history;
(6) Patients with chronic kidney disease and severe heart, lung, liver and other vital organ dysfunction;
(7) Patients with severe uncontrolled hypertension (systolic blood pressure >=180mmHg or diastolic blood pressure >=110mmHg);
(8) Severe arrhythmia (ventricular bisection, ventricular tachycardia, ventricular fibrillation, third degree atrioventricular block, cardiac Cardiac arrest, severe sinus tachycardia and bradycardia, sick sinus syndrome, reentrant supraventricular tachycardia, arrhythmia leading to hemodynamic changes);
(9) allergic constitution, or more People who are allergic to foods of various drugs, or those who are known to be allergic to the components of the drug;
(10) Patients who have participated in other clinical trials or are taking other proprietary Chinese medicines within one month;
(11) Patients who are pregnant, preparing to become pregnant, and breastfeeding Women;
(12) Patients with mental, psychological and other problems that do not match the completion of the study.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified