effect of lavender in Alzheimer's disease patients
- Conditions
- Alzheimer's disease.Alzheimer's disease
- Registration Number
- IRCT20200720048149N1
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Alzheimer's patients in stage 1 and 2, whose diagnosis of Alzheimer's disease is based on ICD10 / DSM-IV criteria. These criteria include: 1- Multiple cognitive deficits that include memory impairment and at least one of the signs of aphasia, apraxia, agnosia and executive dysfunction, 2- Existence of cognitive deficits severe enough to cause occupational and social dysfunction and show Provides a reduction in the previous performance level.
End-stage patients of Alzheimer's disease
According to ICD10 / DSM-IV criteria, patient with a cognitive impairment is excluded from the study if dementia is not diagnosed in the delirium period.
Patients with cognitive deficits are due to other central nervous system diseases such as Parkinson's, or systemic diseases such as hypothyroidism and substance abuse.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Mini–Mental State Examination (MMSE) score. Timepoint: At the beginning of the study and after one month of intervention. Method of measurement: Mini–Mental State Examination.;Alteration of blood metabolites. Timepoint: Before the intervention and one month after the intervention. Method of measurement: Nuclear magnetic resonance (NMR) device.;Altered urinary metabolites. Timepoint: Before the intervention and one month after the intervention. Method of measurement: Nuclear magnetic resonance (NMR)device.
- Secondary Outcome Measures
Name Time Method Awareness of time. Timepoint: Before the intervention and one month after the intervention. Method of measurement: With MMSE test score.;Awareness of location. Timepoint: Before the intervention and after a month. Method of measurement: With MMSE test score.;Memory. Timepoint: Before the intervention and after a month. Method of measurement: With MMSE test score.;Attention and calculation. Timepoint: Before the intervention and after a month. Method of measurement: With MMSE test score.