Novel Approach for Embryo Transfer Medium by Adding Cytokine to Hyaluronan Enriched Embryo Transfer Medium (Embryo Glue)
- Conditions
- Infertility
- Interventions
- Other: Cytokine group
- Registration Number
- NCT02422134
- Lead Sponsor
- Ibn Sina Hospital
- Brief Summary
It was proven that the Cytokine granulocyte-Macrophage clony stimulating factor had been found naturally in reproductive tract so our target is to test its effect if added to embryo transfer medium.
- Detailed Description
The IVF embryo transfer media design and upgrade underwent many ideas during the last 3 decades, we suppose that adding Cytokine GM-CSF as an endometrial modifier to already proven successful medium hyaluronan enriched medium to test the efficacy ipon pregnancy and implantation rate in vitro so we decide to design a trial to compare the clinical outcome by sibling embryo to be transferred into 2 groups and the same culture condition but with one arm with Cytokine and the other is traditional one and closely monitor the outcome within the 2 arms and record the results.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Female
- Target Recruitment
- 400
- all patients
- above 40 years old
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Cytokine plus Hyalurinan embryo transfer arm Cytokine group To monitor the pregnancy and implantation of the patients in this arm after adding Cytokine to the embryo transfer medium.
- Primary Outcome Measures
Name Time Method Pregnancy rate ( % ) 9 months
- Secondary Outcome Measures
Name Time Method Implantation rate ( % ) 9 months
Trial Locations
- Locations (2)
Ibnsina IVF center
🇪🇬Sohag, Egypt
Banon IVF center
🇪🇬Assiut, Egypt