ACTRN12616000709448已完成未知
Investigation of endothelial toxicity after allogeneic haematopoietic stem cell transplantation
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 16 Years 至 70 Years（—）
- 性别
- All
入选标准
- •1.Completed work-up and planned to proceed with allogeneic HSCT at Fiona Stanley Hospital
- •2.Has had sufficient work-up to enable haematopoietic cell transplantation-specific comorbidity index (HCT-CI) to be calculated (minimum: history and examination, lung function studies, assessment of cardiac ejection fraction)
- •3.Will receive one of the following conditioning regimens: busulfan + cyclophosphamide, TBI + cyclophosphamide or fludarabine + melphalan
- •4.Will receive GVHD prophylaxis with a calcineurin inhibitor (cyclosporine or tacrolimus) and short course methotrexate, with or without ATG
- •5.Provides informed consent to participate in the study
排除标准
- •1.Incomplete pre-transplant work-up (see inclusion criteria 2 above)
- •2.Will receive a conditioning regimen or GVHD prophylaxis regimen other than those specified in the inclusion criteria
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