Effect on the vascular endothelium function of aggressive lipid control treatment with rosuvastatin -evaluation of a vascular endothelium function by Endo-PAT 2000- - EARTH Study

Division of Cardiology, Department of Internal Medicine, Nihon University School of Medicine0 个研究点目标入组 50 人开始时间: 2013年3月1日最近更新: 2023年10月17日

适应症

试验速览

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•1) Patients within 72 hr after the incidence of acute myocardial infarction. 2) Patients to be required the revascularization within 48 hours. 3) Familial hypercholesterolemia or secondary hypercholesterolemia 4) Patients with the value over 400mg/dL of fasting serum triglyceride. 5) Patients with history of hypersensitivity to statin. 6) Severe diabetes patients whose hemoglobin A1c are > 8.5%. 7) Active hepatic disease patients with > 100 IU/L of either ALT or AST, or with > 2.5 mg/dL of total bilirubin. 8) Patients with either <30 ml/min of creatinine clearance or > 2.0 mg/dL of serum creatinine. 9) Patients receiving cyclosporine. 10) Patients during pregnancy and with pregnant possibility. 11) Patients with hypothyroidism, hereditary myopathy (such as muscular dystrophy), a family history or a history of muscle disorder resulted from drug. 12) Patients with drug abuse or alcohol addiction. 13) Patients who are judged ineligible for any other reasons by the investigator.

发起方

Division of Cardiology, Department of Internal Medicine, Nihon University School of Medicine