Determination of Risk Factors and Mortality for Pediatric Chronic Critical Illnes in Turkey: Multicenter Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 888
- 试验地点
- 1
- 主要终点
- Critical care unit mortality
研究概览
简要总结
It is predicted that the number of Pediatric Chronic Critical Illness increases similar to adult all over the world. The prevalence of Pediatric Chronic Critical Illness in Turkey is unknown. The investigators aimed to evaluate the etiology, comorbid conditions, demographic data, prevalence, mortality and costs of these patient in intensive care units in Turkey. In this multi-centered study, The investigators will retrospectively review the last 3 year of patients receiving treatment at the Intensive Care Unit.
详细描述
Patients receiving acute critical cause of ICU in the Intensive Care Unit (ICU) may be hospitalized for longer periods of time due to accompanying diseases or iatrogenic causes. This disease is called "Chronic Critical Illness" (CCI). CCI is associated with prolonged acute mechanical ventilation, but there is no definition in the literature for newborns. Pediatric CCI is estimated to be similar to adults. In the United States, the number of CCI is around 250,000, which is estimated to have doubled in the last 10 years. 50% of patients die in one year and much less than 12% recover. The estimated annual cost for the CCI in the United States is over $ 20 billion. The prevalence of Pediatric CCI in Turkey is unknown. In this study, it was aimed to investigate risk factors, mortality and cost of children with chronic critically ill and newborn patients in intensive care units in Turkey.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Chronic Critical IIlness
- •The patients who are younger than 18 years old and staying in ICU for at least 14 days.
- •(The patients who is newborn and stay in the intensive care unit for 30 days in addition to prematurity).
- •At least one of the additional criteria;
- •Prolonged acute mechanical ventilation
- •Tracheostomy
- •Severe wound (burn) or trauma
- •Encephalopathy (Post resuscitation syndrome, Asphyxia, Intra-cranial hemorrhage, Metabolic disease, etc.)
- •Traumatic brain injury
- •Status epilepticus
- •Post operative (Cardiac and noncardiac)
- •Neuromuscular disease (Spinal Muscular Dystrophy, Cerebral Palsy, Muscular Dystrophy)
排除标准
- •Patients with a disease other than a chronic critical disease
- •Patients older than 18 years
结局指标
主要结局
Critical care unit mortality
时间窗: 30 Day, 90 Day, 180 Day, 365 day
The mortality change rates in the 30th Day, 90th Day, 180th Day, 365th Day
次要结局
- Critical care unit costs for infant patients(Duration of intensive care unit stay (From 14 day to 1 years after hospitalization))
- Critical care unit costs for premature newborn(Duration of intensive care unit stay (From 1 month to 1 year after hospitalization))
研究者
Hilmi Demirkiran, MD
Assistant Professor
Yuzuncu Yıl University