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Clinical Trials/NCT04464330
NCT04464330
Unknown
N/A

Biomechanical Mechanism of the Change of the Gait Touch Information After ACL Rupture

Peking University Third Hospital1 site in 1 country110 target enrollmentApril 2, 2017

Overview

Phase
N/A
Intervention
Not specified
Conditions
Anterior Cruciate Ligament Injuries
Sponsor
Peking University Third Hospital
Enrollment
110
Locations
1
Primary Endpoint
the moment of knee flexion in the gait cycle
Last Updated
5 years ago

Overview

Brief Summary

High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.

To clarify the mechanism between the biomechanical status of knee joint and the change of gait touch information, and to provide scientific basis for quantifying and evaluating the biomechanical status of knee joint in dynamic load-bearing state.

Detailed Description

The purpose of this study is to identify the characteristics of the disease, diagnose the disease by computer and evaluate the rehabilitation based on gait touch information after ACL rupture and reconstruction, combined with the methods of multi-body dynamics, machine learning and biomechanics analysis. Methods: 55 healthy volunteers, 55 patients with ACL rupture were recruited. Three dimensional gait analysis and dynamic plantar pressure were used to test the kinematic and dynamic data of lower limbs and gait touch information when walking, jogging, stopping and jumping, and running side cutting. Outcome evaluation indexes and statistical methods: the following indexes were measured repeatedly by two factor ANOVA method, and the left and right sides and different rehabilitation time were used as the variables of repeated measurement: the biomechanics of the lower limb joint and the change of the biological characteristics of gait touch information were analyzed. To study the biomechanical status of different knee joints and the mechanism of the change of gait touch information. Finally, based on the information of gait touch, a biomechanical evaluation model of knee joint during walking or jogging is established, which provides the exact basis for quantifying and evaluating the biomechanical state of knee joint under the dynamic load-bearing state of gait touch information.

Registry
clinicaltrials.gov
Start Date
April 2, 2017
End Date
December 30, 2020
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18-35 years old
  • Patients who have isolated ACL injury and receive ACL reconstruction surgery at Peking University Third Hospital.
  • With isolated ACL injury (an ACL injury with no need for surgical repairs to other knee structures).
  • All participants have no known disorders or diseases other than ACL rupture.

Exclusion Criteria

  • Cognitive impairment
  • Other injuries affecting movement performance.

Outcomes

Primary Outcomes

the moment of knee flexion in the gait cycle

Time Frame: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

walking speed

Time Frame: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

knee flexion angle

Time Frame: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

the moment of knee extension in the gait cycle

Time Frame: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

ground reaction force

Time Frame: On the day of enrollment.

Three-dimensional gait analysis system and plantar pressure were used during walking, jogging, cutting and jumping.

Secondary Outcomes

  • The International Knee Documentation Committee (IKDC) score(On the day of enrollment.)

Study Sites (1)

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