effects of propranolol and levetiracetam to prevent migraine attacks in children 5-15 year-old childre

Not Applicable

Recruiting

• Conditions: Migraine.; Migraine

• Registration Number: IRCT20090412001808N5
• Lead Sponsor: Sari University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age 5 to 15 years
migraine attacks
headache more than once a week
Headache causing a child's disability (PedMIDAS score more than 20)
Headache prophylaxis is required in the child

Exclusion Criteria

Underlying diseases such as asthma, liver disease, diabetes
Secondary headaches or other neurological disorders such as epilepsy
receiving medications for migraine over the past two months
History of sensitivity to propranolol and levetiracetam
history of propranolol and levetiracetam for migraine prophylaxis
renal dysfunction

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Headache severity. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: Visual Analogue Scales (From a score of 1-10 that is scored by the child).;Headache duration. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: minute.

Secondary Outcome Measures

Name	Time	Method
umber of migraine attacks per month. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: Number in the questionnaire.;Side effects of medication (Dizziness, drowsiness, weight loss, anorexia, memory impairment, imbalance, skin complications). Timepoint: The 3rd month and 6th month. Method of measurement: Questionnaire.;Severity of disability due to headache. Timepoint: The beginning of the study, the 3rd month and the 6th month. Method of measurement: Questionnaire (Grade 1: Score 0-10, Grade 2: Score 11-30, Grade 3: Score 31-50 and Grade 4: Scores above 50).