Urinary and Sexual Function Before and After Surgical Decompression of Cervical Myelopathy

• Conditions: Psychosexual Dysfunctions; Myelopathy; Sexual Arousal Disorder; Neurogenic Bladder; Erectile Dysfunction

• Registration Number: NCT02059798
• Lead Sponsor: The Catholic University of Korea

Brief Summary

Hypotheses:

Decompressive surgery of cervical myelopathy will improve bladder function.

Decompressive surgery of cervical myelopathy will improve sexual function.

Detailed Description

The investigators will enroll consecutive cohort with cervical myelopathy who are scheduled to take surgical decompression of cervical spinal cord, aged between 25 and 65.

The exams for the patients include followings

* JOA (Japanese Orthopaedic Association) Scores for cervical myelopathy

* VAS (Visual Analog Scale) pain score

* IPSS (International Prostate Symptom Score) and IIEF (International Index of Erectile Function) in male patients

* FSFI (Female Sexual Function Index) and UDI (Urinary Distress Inventory) in female patients

* Bladder compliance, Detrusor leak point pressure, Peak detrusor pressure

* Rigidity activity unit of penis

Study Timeline

• Status Verified: 2014-02
• Study First Submitted: 2014-02-07
• Study First Submitted QC: 2014-02-10
• Last Update Submitted: 2014-02-10
• Study First Posted: 2014-02-11
• Last Update Posted: 2014-02-11
• Study Start: 2014-03
• Primary Completion: 2016-02
• Study Completion: 2016-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 76

Inclusion Criteria

• evidence of progression of motor or sensory nerve
• cervical myelopathy in magnetic resonance imaging

Exclusion Criteria

• radical pelvic surgery
• pelvic irradiation
• evidence of brain damage (dementia, cerebrovascular disease)
• evidence of psychotic disorder

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
JOA (Japanese Orthopaedic Association) Scores for cervical myelopathy	6 months after surgery	This score will provide patients' conditions at a glance.

Secondary Outcome Measures

Name	Time	Method
Bladder compliance	6 months after surgery	This will be provided by urodynamic study, and will show the intactness of Guarding reflex from upper spinal cord tract.

Trial Locations

Locations (1)

St. Vincent's Hospital, The Catholic University of Korea; 🇰🇷 Suwon, Gyeonggi-do, Korea, Republic of