Skip to main content
Clinical Trials/NCT06335524
NCT06335524
Recruiting
N/A

Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants: A Randomized Clinical Trial

University of Alabama at Birmingham1 site in 1 country188 target enrollmentNovember 1, 2024

Overview

Phase
N/A
Intervention
Not specified
Conditions
Child Development
Sponsor
University of Alabama at Birmingham
Enrollment
188
Locations
1
Primary Endpoint
ASQ-3 scores
Status
Recruiting
Last Updated
4 months ago

Overview

Brief Summary

This study will test the hypothesis that in preterm infants a caregiver-implemented early developmental intervention (EDI) using finger puppets to develop joint attention and encourage interactive communication with routine EDI care including Bookworm training compared with routine EDI care including Bookworm training alone will increase the Ages and Stages Questionnaire® score at 12 months corrected age.

Registry
clinicaltrials.gov
Start Date
November 1, 2024
End Date
December 1, 2028
Last Updated
4 months ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Colm Travers

Associate Professor

University of Alabama at Birmingham

Eligibility Criteria

Inclusion Criteria

  • inborn at UAB, delivered at less than 34 weeks' gestation, 32-39 weeks' PMA, off sedatives, and off invasive respiratory support.

Exclusion Criteria

  • a major malformation, a known syndrome, enrolled in a competing trial targeting neurodevelopmental outcomes as a primary outcome.

Outcomes

Primary Outcomes

ASQ-3 scores

Time Frame: 12 months corrected age

Ages and Stages Questionnaires 3rd Edition

Secondary Outcomes

  • Edinburgh Postnatal Depression Scale(6 months)
  • ASQ scores below -2SD(24 months corrected age)
  • ASQ-3 scores(24 months corrected age)
  • Severe neurodevelopmental impairment(24 months corrected age)
  • Language Composite Score on BSID-IV(24 months corrected age)
  • ASQ scores below -1SD(24 months corrected age)
  • ASQ-SE2 scores(24 months corrected age)
  • Moderate or severe neurodevelopmental impairment(24 months corrected age)
  • Cognitive Composite Score on BSID-IV(24 months corrected age)
  • Motor Composite Score on BSID-IV(24 months corrected age)
  • MCHAT score(24 months corrected age)

Study Sites (1)

Loading locations...

Similar Trials