Integrated Multidisciplinary Care for Parkinson's Disease: a Controlled Trial
- Conditions
- Parkinson's Disease
- Interventions
- Other: Multidisciplinary CareOther: Usual Care
- Registration Number
- NCT00518791
- Lead Sponsor
- Radboud University Medical Center
- Brief Summary
The aim of the present study is to evaluate the (cost) effectiveness of a new health care system in which an individualised multidisciplinary assessment is given to patients with Parkinson's Disease(PD)in combination with treatment by a dedicated team of specifically trained health professionals, compared to usual care. Overall, we anticipate to gain more insight in the clinical effectiveness and health care costs of multidisciplinary treatment in PD.
- Detailed Description
PD is a complex disorder, with motor as well as non-motor symptoms. Despite the complexity of PD, management of the disease is often 'monodisciplinary' since most patients are only treated by a neurologist. Stimulating compensatory strategies by allied health professionals might offer additional therapeutic relief, but this assumption is mainly based on theoretical arguments and expert opinion. Even less is known about the claim that a multidisciplinary team of multiple professionals active in complementary domains (e.g. physiotherapy, occupational therapy and speech therapy) is superior to management by each of these professionals alone.
This study anticipates to provide more insight in the clinical effectiveness and health care costs of multidisciplinary treatment in PD. Therefore, our multidisciplinary care concept (a comprehensive assessment by a dedicated multidisciplinary team and subsequent treatment by specifically trained health professionals) that is tailored to the patients' individual needs will be compared to usual care in terms of effectiveness and costs.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 301
- Patients with Idiopathic PD, diagnosed according to the Brain Bank Criteria of the UK Parkinson's Disease Society
- Regular control by the neurologist
- Living independently in the community
- Able to complete the trial questionnaires
- Atypical parkinsonian syndromes
- Hoehn and Yahr stage 5
- Severe cognitive impairment (MMSE<24)
- Presence of other neurological disorders
- Severe co-morbidity (e.g. cancer)
- Planned surgical procedure for PD within the intervention period
- Patients who have already visited the Multidisciplinary Assessment Center
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description I Multidisciplinary Care Multidisciplinary Care II Usual Care Usual Care
- Primary Outcome Measures
Name Time Method Parkinson's Disease Quality of Life Questionnaire (PDQL) 8 months AMC Linear Disability Score (ALDS) 8 months
- Secondary Outcome Measures
Name Time Method SF-36 (secundary;utility score) 8 months UPDRS Motor Examination (part III)(secondary) 4 months UPDRS Complications of therapy (part IV)(tertiary) 4 months SPDDS(tertiary) 8 months Modified MACTAR scale(tertiary) 8 months Parkinson Activity Scale(tertiary) 4 months Costs (secondary) 8 months Frequency of falls (tertiary) 8 months Freezing of Gait Questionnaire (tertiary) 8 months Falls Efficacy Scale (tertiary) 8 months Non-Motor Symptom Assessment Scale and Quest for Parkinson's Disease (tertiary) 8 months (Quest) and 4 months (Scale) Hospital Anxiety and Depression Scale (tertiary) 8 months Caregiver burden assessed with BELA-A-k (secondary), SF-36 (tertiary), and HADS (tertiary) 8 months
Trial Locations
- Locations (6)
Ziekenhuis Rijnstate
🇳🇱Arnhem, Netherlands
Ziekenhuis Groep Twente, Twenteborg Ziekenhuis
🇳🇱Almelo, Netherlands
Medisch Centrum Leeuwarden
🇳🇱Leeuwarden, Netherlands
Canisius Wilhelmina Ziekenhuis
🇳🇱Nijmegen, Netherlands
Ziekenhuis Groep Twente, Streekziekenhuis Midden-Twente
🇳🇱Hengelo, Netherlands
Wilhelmina Ziekenhuis Assen
🇳🇱Assen, Netherlands