Does Topical Lidocaine Decrease Sweat During Exercise in the Heat?

Not Applicable

Completed

• Conditions: Sweat Pore Closure
• Interventions: Drug: Lidocaine; Other: control

• Registration Number: NCT05379283
• Lead Sponsor: San Diego State University

Brief Summary

Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control.

Detailed Description

Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control. Sweat will be collected via macroducts attached to each arm. Sweat production on each arm will be compared using t-tests.

Study Timeline

• Study First Submitted: 2022-05-11
• Study Start: 2022-05-15
• Study First Submitted QC: 2022-05-16
• Study First Posted: 2022-05-18
• Primary Completion: 2022-09-15
• Study Completion: 2022-09-15
• Status Verified: 2024-08
• Last Update Submitted: 2024-08-27
• Last Update Posted: 2024-08-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

18-35 years of age -

Exclusion Criteria

pregnant females

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
lidocaine pretreated skin	Lidocaine	one arm will be pretreated with lidocaine before exercise in the heat
lidocaine pretreated skin	control	one arm will be pretreated with lidocaine before exercise in the heat

Primary Outcome Measures

Name	Time	Method
volume of sweat produced during exercise following topical lidocaine	one hour of exercise	Volume of sweat produced during exercise following tipocal lidocaine

Trial Locations

Locations (1)

San Diego State University; 🇺🇸 San Diego, California, United States