Metabolism and Oxygen Consumption During Functional Electrical Stimulation Cycling in COPD

Phase 3

Completed

• Conditions: COPD
• Interventions: Device: FES-cycling; Device: Classic cycloergometer

• Registration Number: NCT02594722
• Lead Sponsor: University Hospital, Rouen

Brief Summary

Chronic Obstructive Pulmonary Disease (COPD) had systemic repercussion and lead to peripheral muscular dysfunction. Muscular atrophy limits aerobic capacity and is a major limitation of daily activity and quality of life. Technologies likes' neuromuscular electrical stimulation (NMES) are currently being adapted and tested to support exercise training.

The investigators hypothesized that functional electrical stimulation cycling improves VO2 and aerobic capacities during exercise compared to endurance training.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2015-10-29
• Study First Submitted QC: 2015-10-31
• Study First Posted: 2015-11-03
• Study Start: 2016-04
• Status Verified: 2017-04
• Primary Completion: 2017-04
• Study Completion: 2017-04
• Last Update Submitted: 2017-04-17
• Last Update Posted: 2017-04-18

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 25

Inclusion Criteria

• COPD (Stade II, III or IV)
• Inform consent

Exclusion Criteria

• Pulmonary rehabilitation contraindication
• Patient with Pacemaker
• Patient in acute exacerbation
• Patient with neurologic comorbidity
• Anemiae

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
One single arm group	Classic cycloergometer	COPD included in a pulmonary rehabilitation program Intervention: Investigators used a bedside cycloergometer with electrical stimulation. COPD perform 2 measure of oxygen uptake during exercise for compare aerobic capacities: * Functional Electrical Stimulation Cycling (FES-cycling) * Classic Cycloergometer endurance training with a sham electrical stimulation
One single arm group	FES-cycling	COPD included in a pulmonary rehabilitation program Intervention: Investigators used a bedside cycloergometer with electrical stimulation. COPD perform 2 measure of oxygen uptake during exercise for compare aerobic capacities: * Functional Electrical Stimulation Cycling (FES-cycling) * Classic Cycloergometer endurance training with a sham electrical stimulation

Primary Outcome Measures

Name	Time	Method
oxygen uptake (VO2)	during 30 minutes exercise

Secondary Outcome Measures

Name	Time	Method
Ratio Ventilation/VO2 (Ventilation equivalent for oxygen)	during 30 minutes exercise	Number of liters of air must be ventilated to consume 1 liter of O2
cardiac output	during 30 minutes exercise
Muscular fatigue	after 30 minutes exercise
Ratio Ventilation/VCO2 (Ventilation equivalent for carbon dioxide)	during 30 minutes exercise	Number of liters of air must be ventilated to reject 1 liter of CO2

Trial Locations

Locations (1)

Medrinal; 🇫🇷 Montivilliers, France