Effect of Helicobacter pylori eradication on functional dyspepsia
Phase 2
- Conditions
- functional dyspepsia.Functional dyspepsia
- Registration Number
- IRCT20140519017756N37
- Lead Sponsor
- Birjand University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 117
Inclusion Criteria
Patients with functional dyspepsia who present abdominal perineal, heartburn, nausea, vomiting, or upper abdominal pain, and some patients with early fullness
absence of organ diseases such as gastroesophagitis, ulcer, and gastric and endometrial cancers according to endoscopy
no history of gastric surgery
no history of eradicating Helicobacter pylori
positive results for Helicobacter pylori infection according to endoscopy
Exclusion Criteria
Patients who fail to complete treatment
Intolerance for anti-Helicobacter pylori antibiotics
Withdrawal from the study for any reason
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Eradication of Helicobacter pylori. Timepoint: At the end of the intervention. Method of measurement: Urease breathing test.;Response to treatment. Timepoint: Before and after intevention. Method of measurement: Endoscopy.
- Secondary Outcome Measures
Name Time Method Diarrhea. Timepoint: After intervention is finished. Method of measurement: Questioning the patient.;Skin rash. Timepoint: After intervention is finished. Method of measurement: Physical examination and questioning the patient.;Severe headache. Timepoint: After intervention is finished. Method of measurement: Physical examination and questioning the patient.;Dry mouth. Timepoint: After intervention is finished. Method of measurement: Physical examination and questioning the patient.;Nausea and vomiting. Timepoint: After intervention is finished. Method of measurement: Physical examination and questioning the patient.;Bitter mouth. Timepoint: After intervention is finished. Method of measurement: Physical examination and questioning the patient.;Stomachache. Timepoint: After intervention is finished. Method of measurement: Physical examination and questioning the patient.