The effects of hypo-caloric and full-caloric enteral feeding on metabolic stress indices of patients with multiple trauma, during the first week of admission in the general intensive care unit

Not Applicable

Recruiting

• Conditions: multiple truama.; Injury, poisoning and certain other consequences of external causes; S00-T98

• Registration Number: IRCT20191124045482N1
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

age between 18-65 years
Gastrointestinal tract with normal function and indications of Enteral Nutrition
Diagnosis of moderate to severe trauma based on GCS (4-14)
Enteral ability to feed in the first 24 to 48 hours of admission
Completion of informed consent form from patients' first-degree reletives

Exclusion Criteria

failure to start enteral nutrition during the first 48 hours of admission
Presence Cancer, diabetes, and cardiovascular disease
pregnancy
Patients who are less than 96 hours in intensive care unit

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
24 hours urea urine. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Triglyceride. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Serum lactate. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Blood Glucose. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Auto-analyzer.;Body temperature. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Rectal temperature measurement using mercury thermometer.;Resting energy expenditures. Timepoint: at the baseline, 7 and 14 days after intervention. Method of measurement: Indirect calorimetric device.

Secondary Outcome Measures

Name	Time	Method
Mid arm circumference. Timepoint: At the baseline and 14 days after starting intervention. Method of measurement: Measuring meters.;Gastrointestinal intolerance. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Calorie intake. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Protein intake. Timepoint: Every day for two weeks. Method of measurement: questionnaire.;Number of hospital admissions days. Timepoint: Followed for 28 days. Method of measurement: questionnaire.