Erythrocyte Omega-3 Fatty Acid Content in Elite Athletes in Response to Omega-3 Supplementation: A Dose-Response
试验速览
- 阶段
- 早期 1 期
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 主要终点
- fatty acid levels at the membrane of the red blood cells
研究概览
简要总结
A suitable concentration of omega-3 fatty acids in relation to omega 6 is considered necessary for a good cell function and prevention of various inflammatory processes. Diet and supplementation are the fundamental procedures to achieve the reference values for several years. Athletes are individuals under physical stress and higher tissue restoration, while maintaining adequate diets they show, as the rest of humans, lower than desired levels. In the present study the investigators aims to determine the modification of those levels by the administration of two different doses of a given product, keeping the same model of diet and physical and competition.
详细描述
The study aims to assess concentrations of the different fatty acids in the erythrocyte membrane before and after administration of a compound with high quality omega3 (EPA and DHA) in two different doses, compared with control group . The period of evaluation and management is four months, one month for the proposed renewal of red blood cells. The composition of the diet, the sports calendar, caloric expenditure and level of training is determined. During the study process it is excluded subjects with injuries or disease processes and ensure that no one take any supplement or modify workouts or diet.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy, young men and women athletes from the Olympic Training Center (OTC) of Sant Cugat del Valles in Barcelona (Spain) (20 to 45 years of age) belonging to different summer sport activities were asked to participate.
排除标准
- •Any type of inflammatory process, or the use of anti-inflammatory medications, consumption of n-3 Fatty Acids (FA) supplements and n-3 FA-supplemented foods in the past 3 months; planning to change dietary habits, or training schedule.
- •During the study, any subject that falls under injury or need nonsteroidal antiinflammatory drug or get sick by inflammatory or infectious disease.
研究组 & 干预措施
2 Gums
Athletes that continued their usual training and diet, who took 2 gums of omega 3 (DHA 760 mg) during the experimental period.
干预措施: 2 Gums (Dietary Supplement)
3 Gums
Athletes that continued their usual training and diet, who took 3 gums of omega 3 (DHA 1140 mg) during the experimental period.
干预措施: 3 Gums (Dietary Supplement)
Control
Athletes and coaches that continued their usual training and diet, but did not take any supplements during the experimental period.
结局指标
主要结局
fatty acid levels at the membrane of the red blood cells
时间窗: Four months
Evaluation will be obtained before and after the experimental period
次要结局
- Different level of impregnation of the red blood cells in relation to dosage and different previous omega 3 index of the athletes(Four months)
- Different level of impregnation of the red blood cells in relation to dosage and weight of the athletes(Four months)
- Impregnation in relation to dosage administrated to the athletes(Four months)
- Different level of impregnation of the red blood cells in relation to dosage and different age of the athletes(Four months)
- Different level of impregnation of the red blood cells in relation to dosage and different sex of the athletes(Four months)
研究者
FRANCISCO DROBNIC, MD, PhD
MD PhD
Centre d'Alt Rendiment