Efficacy and Safety of TMS and Deep TMS Treatment for Psychiatric and Neurological Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 228
- 试验地点
- 2
- 主要终点
- the proportion of patients who experienced complete remission of the disease
研究概览
简要总结
The goal of this study is to examine the efficacy and safety of transcranial magnetic stimulation (TMS) and deep TMS (dTMS) for treatment of different psychiatric and neurological disorders. Subjects will be randomized into two groups: experimental (treated with pharmacotherapy and TMS) and control group (treated only with pharmacotherapy). They and their clinicians will complete a battery of instruments that measure relevant symptoms, global functioning and quality of life. The first measurement will be done after the inclusion and before treatment. The second measurement will be made immediately after the end of treatment (after 4 weeks). The other measurements (follow-up) will be made after 3 and 6 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 30 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •diagnosed psychiatric or neurological disorder, duration of disorder for at least 5 years, inpatients or outpatients treated in Psychiatric hospital Sveti Ivan
排除标准
- •suicidality, psychosis, alcohol addiction, unable to complete the questionnaires
研究组 & 干预措施
TMS
The experimental group will be treated with transcranial magnetic stimulation for 4 weeks.
干预措施: TMS (Device)
noTMS
The control (no intervention) group will be treated as usual (with pharmacotherapy). These patients will receive TMS treatment after data collection is ended.
结局指标
主要结局
the proportion of patients who experienced complete remission of the disease
时间窗: up to six months
Measurement points: immediately after the end of treatment, and follow-up after 3 and 6 months.
次要结局
未报告次要终点