Influencing Factors in Patients With Colorectal and Gastric a Retrospective Study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Polyp, Colonic
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
- Enrollment
- 64889
- Locations
- 1
- Primary Endpoint
- Influencing factors in patients with colorectal polyps: a retrospective study
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
The identification of risk factors of colorectal/gastric polyp is more helpful for preventing colorectal cancer. And modifiable factors (such as high-fat diet, abnormal blood lipid, smoking, lack of exercise, obesity), and unmodifiable factors (including age, gender, race, familial adenomas, genetic)) can affect the risk of polyps. Thus early studying risk factors are the key to improving prognosis. what's more, early detection and timely treatment have important clinical significance for preventing and reducing the occurrence of gastrointestinal cancer.
Detailed Description
Colorectal cancer (CRC) is the third most common cancer in the world. what's more, CRC is therefore an important public health concern in China due to its rising incidence and prevalence, in addition to the burden of disease. There is robust evidence indicating that early detection by screening and removal of cancer precursor lesions offers an effective method of reducing colorectal cancer morbidity and mortality. Studies have shown that colorectal polyps are considered to be related to colorectal cancer, especially adenoma .The primary aim of this study was to identify high risk features of multiple polyps based on size, location and histological type. Patient age and gender were also characterized on the basis of a contingency analysis of a large series of Chinese patients with colorectal polyps. These data provide important information on risk factors associated with multiple polyps, which will serve as evidence for an individualized approach to colonoscopy screening guidelines in China. Similarly, recent years, with the widespread use of gastroscopy, people's health awareness and lifestyle changes, more and more people have performed gastroscopy, so a large number of patients with gastric polyps can be found in the clinic. Gastric polyps are raised lesions that originate in the mucosal layer or submucosa and protrude into the stomach cavity. According to their pathological characteristics, they can be divided into two categories: mucosal layer and non-mucosal layer.Gastric polyps originating from mucosal layers, represented by natural, fundus glandular and adenomatous polyps, are the most common in clinical practice, while non-mucosal polyps including gastric stromal tumors and inflammatory fibrous polyps are more common in clinical practice. Although the incidence of gastric polyps is far less than that of intestinal polyps, some pathological types, especially adenomatous polyps, have obvious malignant potential and are recognized as precancerous lesions . Therefore, we retrospectively analyzed the records of patients with gastrointestinal polyps in our hospital in the past years, and provided epidemiological data to study the factors in polyps.
Investigators
Eligibility Criteria
Inclusion Criteria
- •patients who underwent colonoscopies
Exclusion Criteria
- •(1) Patients with Crohn's disease, inflammatory bowel disease, and colorectal cancer; (2) Patients with ulcerative bowel disease, and intestinal tuberculosis; (3) Patients with history of familial polyposis; (4) All patients without complete endoscopic reports and complete demographics records.
Outcomes
Primary Outcomes
Influencing factors in patients with colorectal polyps: a retrospective study
Time Frame: JUNE 30,2020
risk factors