Prediction of short and long term food challenge outcome in childre
- Conditions
- VoedselallergieFood allergy
- Registration Number
- NL-OMON37019
- Lead Sponsor
- niversitair Medisch Centrum Utrecht
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Withdrawn
- Sex
- Not specified
- Target Recruitment
- 100
- Child is between 1 * 18 years old
- Suspected food allergy for peanut by:
1) Raised specific IgE for peanut and/ or positive skin prick test for peanut without previous known
ingestion of the allergen, or;
2) Objective immediate type clinical signs or symptoms (within 2 hours) after ingestion of peanut or
repetitive subjective clinical signs or symptoms after ingestion of peanut with or without raised
specific IgE for peanut / positive skin prick test for peanut; or
3) Objective immediate type clinical signs or symptoms (within 2 hours) after the ingestion of an unknown allergen and raised specific IgE for peanut / positive skin prick test for peanut.;- Parents of the children must be able to speak, read and write Dutch language
- Peanut is eaten regularly in a substantial amount without clinical signs or symptoms
- A previous severe life treating reaction to peanut requiring ICU submission.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>- Differences between children with positive and children with negative<br /><br>short-term food challenge outcome<br /><br>- Differences between children with positive and children with negative long<br /><br>term food challenge outcome</p><br>
- Secondary Outcome Measures
Name Time Method <p>Clinical parameters measured during challenge to discriminate between children<br /><br>with positive and negative short term food challenge outcome<br /><br>Symptom Scores, VAS-scores, heart rate, saturation, breathing pattern, FEV1,<br /><br>blood pressure, temperature, VAS-scores, dermographism and eczema scores.</p><br>