Perinatal Depression Treatment and Child Development: A Follow-Up of the Thinking Healthy Programme
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Depression
- Sponsor
- Duke University
- Enrollment
- 964
- Locations
- 1
- Primary Endpoint
- Estimate of general intelligence
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
The purpose of this study is to examine whether the successful perinatal depression intervention among mothers (Thinking Healthy Programme, THP) has led to improved developmental outcomes in the children 6 years later. Economic and human resources aspects of the intervention will also be evaluated to determine overall societal benefits from investment in such a program, feasibility of scaling up the intervention and its sustainability in the long-term. The primary hypothesis is that children of mothers who participated in the THP will have better cognitive outcomes and socio-emotional functioning when compared to children of mothers randomized to the control group.
Investigators
Eligibility Criteria
Inclusion Criteria
- •children of women who were eligible to participate in the Thinking Healthy Programme
Exclusion Criteria
- •developmental disability, visual or hearing impairment
Outcomes
Primary Outcomes
Estimate of general intelligence
Time Frame: Re-enrollment visit, approximately 7 years post-intervention
Measures of executive functions
Time Frame: Re-enrollment visit, approximately 7 years post-intervention
Working memory, cognitive flexibility, inhibitory control, and sustained attention will be measured by standard tests of cognitive functioning.
Level of literacy and numeracy
Time Frame: Re-enrollment visit, approximately 7 years post-intervention
Presence of behavioral and emotional problems (socio-emotional development)
Time Frame: Re-enrollment visit, approximately 7 years post-intervention
Secondary Outcomes
- Height-for-age(Re-enrollment visit, approximately 7 years post-intervention)
- Weight-for-age(Re-enrollment visit, approximately 7 years post-intervention)