Elastography in Thyroid Nodule Evaluation
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 55
- 试验地点
- 2
- 主要终点
- Stiffness of Thyroid Nodules as Measured by Elastography
研究概览
简要总结
This clinical trial studies how well ultrasound elastography works in assessing the cancer status of potentially malignant thyroid nodules.
详细描述
PRIMARY OBJECTIVES:
Determine the utility of ultrasound elastography in evaluation of thyroid nodules being evaluated for the presence of cancer.
Elastography measures the passages of ultrasound shear waves through tissue to gauge the stiffness and compressibility of the tissue, collectively "tissue stiffness," and may be a better way to image thyroid nodules. Tissue stiffness is a physiological parameter that is being evaluated for differences between non-cancerous (benign) and cancerous thyroid nodules.
Participants will undergo elastography over the 10 minutes prior to either fine needle aspiration of a biopsy specimen or surgical resection of the thyroid nodule. Tissue specimens from the biopsy specimen or surgical resection will be assessed pathologically to determine actual cancer status.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Presence of a thyroid nodule that is amenable to ultrasound guided fine needle aspiration
排除标准
- •Patients who are unable to lie supine for a biopsy
- •Pregnant patients
结局指标
主要结局
Stiffness of Thyroid Nodules as Measured by Elastography
时间窗: 1 week
Potentially cancerous thyroid nodules will be assessed elastographically, and cancer status will be determined from a fine needle aspiration biopsy results or the surgically excised nodule. The outcome will be reported as median tissue stiffness with standard deviation for nodules that were determined non-cancerous (benign), cancerous, or indeterminate.
次要结局
未报告次要终点
研究者
Aya Kamaya
Professor of Radiology
Stanford University