The effect of pancratic enzyme replacement therapy on anthropometric criteria in children with failure to thrive
Phase 3
Recruiting
- Conditions
- Failure To Thrive in Child.Other lack of expected normal physiological developmentR62.8
- Registration Number
- IRCT20230313057703N1
- Lead Sponsor
- Rasht University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
2-14-year-old patients with failure to thrive whose Z-SCORE weight is below -2.
Exclusion Criteria
type 3 failure to thrive
Type 2 growth disorder that hormonal problems have not been ruled out by an endocrinologist.
cardiovascular diseases
pulmonary diseases
malabsorption
Pancreatic exocrine insufficiency
steatorrhea
renal diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Weight gain. Timepoint: At the beginning and 2 months after. Method of measurement: Weight is measured by a Seca scale (Germany) [this scale is calibrated every day], then the patients will be treated for 2 months and re-examined with the same scale.
- Secondary Outcome Measures
Name Time Method Height raise. Timepoint: at the beginning and 2 months after. Method of measurement: Height is measured by a tape measure from Seka (Germany), standing without shoes and attached to the wall at the beginning and 2 months after treatment.;BMI raise. Timepoint: at the beginning and 2 months after. Method of measurement: BMI is calculated by dividing weight in kilograms by height in square meters.;Z score raise. Timepoint: at the beginning and 2 months after. Method of measurement: By putting weight, height, and BMI in the Medscape calculator software, the Z SCORE number is reported.